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NCT02261961 · ClinicalTrials.gov registry record · NA
Immune Function and Muscle Adaptations to Resistance Exercise in Older Adults
A NA study, sponsored by VA Office of Research and Development.
- Completed
- Registry status
- NA
- Development phase
- 59
- Enrollment target
NCT02261961: Completed NA study, sponsored by VA Office of Research and Development.
NCT02261961 is a NA study that has completed, run by VA Office of Research and Development. The registered enrollment target is 59 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02261961, a NA study, has completed, sponsored by VA Office of Research and Development.
- COMPLETED
- Registry status
- NA
- Development phase
- 59 participants
- Enrollment target
Study Summary
The loss of muscle mass and strength due to aging leads to serious health problems for older adults. Muscle health can be improved by exercise training, but some people improve their strength substantially, whereas others improve little. The reason for this variation is unknown. This study will investigate whether function of the immune system influences how well people respond to exercise. Older Veterans who participate will have their muscle size, strength, and function measured periodically for almost a year. Participants will drink a nutritional supplement or placebo daily and complete a 36 session strength training program. Participants will be vaccinated for tetanus and donate small amounts of blood and muscle tissue during the study so that immune function can be compared to muscle outcomes during training and during a long-term follow-up. The study results should increase the investigators' understanding of the negative effects of aging on muscle and will possibly lead to better strategies for muscle maintenance and rehabilitation for older adults.
Primary Outcome
The change in plasma antibody concentration for response to the pertussis antigen within the tetanus, diphtheria, and pertussis (TDAP) vaccination will be measured between baseline and one week post-vaccination.
Interventions
- OTHER Resistance Exercise Training
- BIOLOGICAL TDAP
- OTHER Acute Resistance Exercise
- OTHER Post-training Follow-up
- DIETARY_SUPPLEMENT Nutritional Supplement (Muscle Armor)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 59 participants |
| Start Date | 2014-07-23 |
| Est. Completion | 2019-09-30 |
| Phase | NA |
What the finished NCT02261961 record still lists
NCT02261961 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 59 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower).
The record links to 0 conditions, and to 5 interventions - of which Resistance Exercise Training is the first listed.
NCT02261961 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02261961 about?
NCT02261961 is a clinical study titled "Immune Function and Muscle Adaptations to Resistance Exercise in Older Adults". The loss of muscle mass and strength due to aging leads to serious health problems for older adults. Muscle health can be improved by exercise training, but some people improve their strength substantially, whereas others improve little. The reason for this variation is unknown. This study will inve...
What is the current status of trial NCT02261961?
This trial is currently completed. It is a NA study. The enrollment target is 59 participants. The study started on 2014-07-23. Estimated completion is 2019-09-30.
What interventions are being tested in trial NCT02261961?
The interventions under investigation include: Resistance Exercise Training (OTHER), TDAP (BIOLOGICAL), Acute Resistance Exercise (OTHER), Post-training Follow-up (OTHER), Nutritional Supplement (Muscle Armor) (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT02261961?
This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02261961's enrollment target sits among peer trials
59 1256th of 2000 higher than 745 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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