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NCT02257242 · ClinicalTrials.gov registry record · Phase 1
Vincristine Sulfate Liposome Injection (Marqibo®), Bendamustine and Rituximab-Phase I Trial in Indolent B-cell Lymphoma
A Phase 1 study, sponsored by Brown University.
- Completed
- Registry status
- Phase 1
- Development phase
- 11
- Enrollment target
NCT02257242: Completed Phase 1 study, sponsored by Brown University.
NCT02257242 is a Phase 1 study that has completed, run by Brown University. The registered enrollment target is 11 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (82% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02257242, a Phase 1 study, has completed, sponsored by Brown University.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 11 participants
- Enrollment target
Study Summary
This study evaluates addition of Vincristine Sulfate Liposome Injection (Marqibo®) to the standard regimen of Bendamustine and Rituximab in adult patients with indolent B-cell lymphoma. This is a dose-escalation study.
Primary Outcome
Determined as the median of the marginal posterior distribution using data from all available patients
Interventions
- DRUG Rituximab
- DRUG Bendamustine
- DRUG Vincristine sulfate liposome injection
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 11 participants |
| Start Date | 2017-05-10 |
| Est. Completion | 2020-11-18 |
| Phase | Phase 1 |
What the finished NCT02257242 record still lists
NCT02257242 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 11 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (82% lower).
The record links to 0 conditions, and to 3 interventions - of which Rituximab is the first listed.
NCT02257242 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02257242 about?
NCT02257242 is a clinical study titled "Vincristine Sulfate Liposome Injection (Marqibo®), Bendamustine and Rituximab-Phase I Trial in Indolent B-cell Lymphoma". This study evaluates addition of Vincristine Sulfate Liposome Injection (Marqibo®) to the standard regimen of Bendamustine and Rituximab in adult patients with indolent B-cell lymphoma. This is a dose-escalation study.
What is the current status of trial NCT02257242?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 11 participants. The study started on 2017-05-10. Estimated completion is 2020-11-18.
What interventions are being tested in trial NCT02257242?
The interventions under investigation include: Rituximab (DRUG), Bendamustine (DRUG), Vincristine sulfate liposome injection (DRUG).
Who is sponsoring clinical trial NCT02257242?
This trial is sponsored by Brown University, which has 231 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02257242's enrollment target sits among peer trials
11 1911th of 2000 higher than 88 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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