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NCT02224872 · ClinicalTrials.gov registry record · Phase 2

Transplantation of Partially Mismatched Related or Matched Unrelated Bone Marrow for Patients With Refractory Severe Aplastic Anemia

A Phase 2 study, sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins.

Completed
Registry status
Phase 2
Development phase
18
Enrollment target

NCT02224872 is a Phase 2 study that has completed, run by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins. The registered enrollment target is 18 participants.

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The verdict

NCT02224872, a Phase 2 study, has completed, sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins.

COMPLETED
Registry status
Phase 2
Development phase
18 participants
Enrollment target

Study Summary

Our primary objective is to determine if it is feasible for SAA patients to be transplanted using non-myeloablative conditioning and post transplantation cyclophosphamide with partially HLA-mismatched donors.

Interventions

  • DRUG Cyclophosphamide
  • DRUG Fludarabine
  • DRUG Thymoglobulin
  • RADIATION TBI
  • PROCEDURE Bone marrow transplant

Trial Details

FieldValue
Enrollment Target 18 participants
Start Date 2014-08
Est. Completion 2021-12
Phase Phase 2

What the Registry Record Tells You About NCT02224872

The ClinicalTrials.gov registry entry for NCT02224872 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 18 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, which has 523 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 5 interventions - of which Cyclophosphamide is the first listed.

NCT02224872 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT02224872 about?

NCT02224872 is a clinical study titled "Transplantation of Partially Mismatched Related or Matched Unrelated Bone Marrow for Patients With Refractory Severe Aplastic Anemia". Our primary objective is to determine if it is feasible for SAA patients to be transplanted using non-myeloablative conditioning and post transplantation cyclophosphamide with partially HLA-mismatched donors.

What is the current status of trial NCT02224872?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 18 participants. The study started on 2014-08. Estimated completion is 2021-12.

What interventions are being tested in trial NCT02224872?

The interventions under investigation include: Cyclophosphamide (DRUG), Fludarabine (DRUG), Thymoglobulin (DRUG), TBI (RADIATION), Bone marrow transplant (PROCEDURE).

Who is sponsoring clinical trial NCT02224872?

This trial is sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, which has 523 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.