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NCT02177695 · ClinicalTrials.gov registry record · Phase 2

S1314, Co-expression Extrapolation (COXEN) Program to Predict Chemotherapy Response in Patients With Bladder Cancer

A Phase 2 study, sponsored by SWOG Cancer Research Network.

Completed
Registry status
Phase 2
Development phase
237
Enrollment target

NCT02177695: Completed Phase 2 study, sponsored by SWOG Cancer Research Network.

NCT02177695 is a Phase 2 study that has completed, run by SWOG Cancer Research Network. The registered enrollment target is 237 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (78% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02177695, a Phase 2 study, has completed, sponsored by SWOG Cancer Research Network.

COMPLETED
Registry status
Phase 2
Development phase
237 participants
Enrollment target

Study Summary

The primary focus of this study is to see if looking at tumor biomarkers using a program called coexpression extrapolation or "COXEN" may predict a patient's response to chemotherapy before surgery.

Primary Outcome

The proportion of participants achieving pT0 in both favorable and unfavorable treatment specific-COXEN score categories. Unit of measure is the number of participants in each category that achieved pT0 \_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_ The relationship of dose-dense methotrexate, vinblastin, do

Interventions

  • DRUG Cisplatin
  • DRUG Doxorubicin
  • DRUG Gemcitabine
  • DRUG Methotrexate
  • DRUG Vinblastine

Trial Details

FieldValue
Enrollment Target 237 participants
Start Date 2014-08-28
Est. Completion 2022-12-01
Phase Phase 2
SWOG Cancer Research Network

270 total trials

What the finished NCT02177695 record still lists

NCT02177695 is an interventional study that assigns participants to a tested intervention. The registered 237 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (78% higher).

The record links to 0 conditions, and to 5 interventions - of which Cisplatin is the first listed.

NCT02177695 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02177695 about?

NCT02177695 is a clinical study titled "S1314, Co-expression Extrapolation (COXEN) Program to Predict Chemotherapy Response in Patients With Bladder Cancer". The primary focus of this study is to see if looking at tumor biomarkers using a program called coexpression extrapolation or "COXEN" may predict a patient's response to chemotherapy before surgery.

What is the current status of trial NCT02177695?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 237 participants. The study started on 2014-08-28. Estimated completion is 2022-12-01.

What interventions are being tested in trial NCT02177695?

The interventions under investigation include: Cisplatin (DRUG), Doxorubicin (DRUG), Gemcitabine (DRUG), Methotrexate (DRUG), Vinblastine (DRUG).

Who is sponsoring clinical trial NCT02177695?

This trial is sponsored by SWOG Cancer Research Network, which has 270 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02177695's enrollment target sits among peer trials

237 255th of 2000 higher than 1,746 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02177695, the US trial registry maintained by the National Library of Medicine. NCT02177695 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.