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NCT02176486 · ClinicalTrials.gov registry record · Phase 1
Safety, Tolerability and Pharmacokinetics of Multiple Rising Doses of Ixazomib in Lupus Nephritis (LN)
A Phase 1 study, sponsored by Takeda.
- Terminated
- Registry status
- Phase 1
- Development phase
- 12
- Enrollment target
NCT02176486: Clinical Trial Phase 1 study, sponsored by Takeda.
NCT02176486 is a Phase 1 study that was terminated before completion, run by Takeda. The registered enrollment target is 12 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (80% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02176486, a Phase 1 study, was terminated before completion, sponsored by Takeda.
- TERMINATED
- Registry status
- Phase 1
- Development phase
- 12 participants
- Enrollment target
Study Summary
The purpose of this study is to characterize the safety and tolerability of ixazomib when administered as multiple oral doses at escalating dose levels in participants with lupus nephritis.
Interventions
- DRUG Placebo
- DRUG Ixazomib
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 12 participants |
| Start Date | 2014-06-09 |
| Est. Completion | 2018-01-19 |
| Phase | Phase 1 |
Why NCT02176486 stopped before completion
NCT02176486 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 12 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (80% lower).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT02176486 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02176486 about?
NCT02176486 is a clinical study titled "Safety, Tolerability and Pharmacokinetics of Multiple Rising Doses of Ixazomib in Lupus Nephritis (LN)". The purpose of this study is to characterize the safety and tolerability of ixazomib when administered as multiple oral doses at escalating dose levels in participants with lupus nephritis.
What is the current status of trial NCT02176486?
This trial is currently terminated. It is a Phase 1 study. The enrollment target is 12 participants. The study started on 2014-06-09. Estimated completion is 2018-01-19.
What interventions are being tested in trial NCT02176486?
The interventions under investigation include: Placebo (DRUG), Ixazomib (DRUG).
Who is sponsoring clinical trial NCT02176486?
This trial is sponsored by Takeda, which has 408 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02176486's enrollment target sits among peer trials
12 1852nd of 2000 higher than 90 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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