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NCT02165345 · ClinicalTrials.gov registry record · Phase 1

Extension Study Evaluating the Safety and Efficacy of Subcutaneous Tocilizumab (RoActemra/Actemra) Administration in Systemic and Polyarticular-Course Juvenile Idiopathic Arthritis

A Phase 1 study, sponsored by Hoffmann-La Roche.

Completed
Registry status
Phase 1
Development phase
82
Enrollment target

NCT02165345 is a Phase 1 study that has completed, run by Hoffmann-La Roche. The registered enrollment target is 82 participants.

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The verdict

NCT02165345, a Phase 1 study, has completed, sponsored by Hoffmann-La Roche.

COMPLETED
Registry status
Phase 1
Development phase
82 participants
Enrollment target

Study Summary

This open-label extension of the JIGSAW studies (WA28117 \[NCT01904279\] and WA28118 \[NCT01904292\]) is designed to evaluate the long-term safety and efficacy of subcutaneous (SC) tocilizumab treatment in participants with polyarticular-course and systemic juvenile idiopathic arthritis (pJIA and sJIA). Participants from the 2 JIGSAW studies will continue to receive 162 milligrams (mg) of SC tocilizumab with treatment schedule according to arthritis subtype and body weight. Participants will receive the treatment until commercial availability of the drug or for a maximum of 5 years, whichever is earlier.

Interventions

  • DRUG Tocilizumab

Trial Details

FieldValue
Enrollment Target 82 participants
Start Date 2014-07-16
Est. Completion 2021-11-24
Phase Phase 1

Sponsor

Hoffmann-La Roche

909 total trials

What the Registry Record Tells You About NCT02165345

The ClinicalTrials.gov registry entry for NCT02165345 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 82 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Hoffmann-La Roche, which has 909 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which Tocilizumab is the first listed.

NCT02165345 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT02165345 about?

NCT02165345 is a clinical study titled "Extension Study Evaluating the Safety and Efficacy of Subcutaneous Tocilizumab (RoActemra/Actemra) Administration in Systemic and Polyarticular-Course Juvenile Idiopathic Arthritis". This open-label extension of the JIGSAW studies (WA28117 \[NCT01904279\] and WA28118 \[NCT01904292\]) is designed to evaluate the long-term safety and efficacy of subcutaneous (SC) tocilizumab treatment in participants with polyarticular-course and systemic juvenile idiopathic arthritis (pJIA and sJ...

What is the current status of trial NCT02165345?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 82 participants. The study started on 2014-07-16. Estimated completion is 2021-11-24.

What interventions are being tested in trial NCT02165345?

The interventions under investigation include: Tocilizumab (DRUG).

Who is sponsoring clinical trial NCT02165345?

This trial is sponsored by Hoffmann-La Roche, which has 909 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.