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NCT02157506 · ClinicalTrials.gov registry record · Phase 2

A Dose Ranging Phase IIa Study of 6 Hour Intravenous Dosages of CXL-1427 in Patients Hospitalized With Heart Failure

A Phase 2 study, sponsored by Bristol-Myers Squibb.

Completed
Registry status
Phase 2
Development phase
70
Enrollment target

NCT02157506: Completed Phase 2 study, sponsored by Bristol-Myers Squibb.

NCT02157506 is a Phase 2 study that has completed, run by Bristol-Myers Squibb. The registered enrollment target is 70 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (47% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02157506, a Phase 2 study, has completed, sponsored by Bristol-Myers Squibb.

COMPLETED
Registry status
Phase 2
Development phase
70 participants
Enrollment target

Study Summary

A randomized, double-blinded, placebo-controlled study of continuous 6-hour IV infusions of CXL-1427 in hospitalized patients with systolic heart failure.

Primary Outcome

A treatment-emergent adverse event (TEAE) was defined as an AE with onset after the start of the study drug infusion at Hour 00:00 through 30 days after the stop of the study drug infusion. All TEAEs and pertinent subsets of TEAEs (e.g., TEAEs with onset during the infusion of study drug, serious TEAEs, etc.) were summarized by system organ class (SOC), preferred term (PT) and treatment group

Interventions

  • DRUG Placebo
  • DRUG CXL-1427

Trial Details

FieldValue
Enrollment Target 70 participants
Start Date 2014-06-30
Est. Completion 2015-07-31
Phase Phase 2
Bristol-Myers Squibb

1,025 total trials

What the finished NCT02157506 record still lists

NCT02157506 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 70 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (47% lower).

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT02157506 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02157506 about?

NCT02157506 is a clinical study titled "A Dose Ranging Phase IIa Study of 6 Hour Intravenous Dosages of CXL-1427 in Patients Hospitalized With Heart Failure". A randomized, double-blinded, placebo-controlled study of continuous 6-hour IV infusions of CXL-1427 in hospitalized patients with systolic heart failure.

What is the current status of trial NCT02157506?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 70 participants. The study started on 2014-06-30. Estimated completion is 2015-07-31.

What interventions are being tested in trial NCT02157506?

The interventions under investigation include: Placebo (DRUG), CXL-1427 (DRUG).

Who is sponsoring clinical trial NCT02157506?

This trial is sponsored by Bristol-Myers Squibb, which has 1,025 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02157506's enrollment target sits among peer trials

70 937th of 2000 higher than 1,036 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02157506, the US trial registry maintained by the National Library of Medicine. NCT02157506 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.