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NCT02152995 · ClinicalTrials.gov registry record · Phase 2
Trametinib in Increasing Tumoral Iodine Incorporation in Patients With Recurrent or Metastatic Thyroid Cancer
A Phase 2 study of Poorly Differentiated Thyroid Gland Carcinoma and Metastatic Thyroid Gland Carcinoma, sponsored by National Cancer Institute (NCI).
- Active
- Registry status
- Phase 2
- Development phase
- 34
- Enrollment target
- 1
- Study location
NCT02152995 is a Phase 2 study of Poorly Differentiated Thyroid Gland Carcinoma and Metastatic Thyroid Gland Carcinoma that is active but no longer recruiting, run by National Cancer Institute (NCI). The registered enrollment target is 34 participants, above the 28-participant average among 6 other Poorly Differentiated Thyroid Gland Carcinoma trials with a reported enrollment target (21% higher). The trial reports 1 study location across 1 state.
The verdict
NCT02152995, a Phase 2 study of Poorly Differentiated Thyroid Gland Carcinoma and Metastatic Thyroid Gland Carcinoma, is active but no longer recruiting, sponsored by National Cancer Institute (NCI).
- ACTIVE NOT RECRUITING
- Registry status
- Phase 2
- Development phase
- 34 participants
- Enrollment target
- 1
- Study location
Study Summary
This phase II trial studies how well trametinib works in increasing tumoral iodine incorporation in patients with thyroid cancer that has come back or spread to another place in the body. Trametinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and may help make treatment with iodine I-131 more effective.
Conditions Studied
Interventions
- PROCEDURE Computed Tomography
- OTHER Laboratory Biomarker Analysis
- OTHER Pharmacodynamic Study
- OTHER Iodine I 124
- RADIATION Iodine I-131
Study Locations (1)
New York
- Memorial Sloan Kettering Cancer Center - New York
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 34 participants |
| Start Date | 2014-08-14 |
| Est. Completion | 2027-02-05 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02152995
The ClinicalTrials.gov registry entry for NCT02152995 describes a study currently listed as active not recruiting, categorized as Phase 2. The registered enrollment target is 34 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 28-participant average among 6 other Poorly Differentiated Thyroid Gland Carcinoma trials with a reported enrollment target (21% higher). The listed sponsor is National Cancer Institute (NCI), which has 3,257 total studies on file at ClinicalTrials.gov.
The record links to 10 conditions, with Poorly Differentiated Thyroid Gland Carcinoma appearing as the primary indexed condition, and to 5 interventions - of which Computed Tomography is the first listed.
NCT02152995 reports 1 study location spanning 1 distinct geographic area - top geographies include New York.
Frequently Asked Questions
What is clinical trial NCT02152995 about?
NCT02152995 is a clinical study titled "Trametinib in Increasing Tumoral Iodine Incorporation in Patients With Recurrent or Metastatic Thyroid Cancer". This phase II trial studies how well trametinib works in increasing tumoral iodine incorporation in patients with thyroid cancer that has come back or spread to another place in the body. Trametinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and may hel...
What is the current status of trial NCT02152995?
This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 34 participants. The study started on 2014-08-14. Estimated completion is 2027-02-05.
What conditions does trial NCT02152995 study?
This clinical trial studies the following conditions: Poorly Differentiated Thyroid Gland Carcinoma, Metastatic Thyroid Gland Carcinoma, Recurrent Thyroid Gland Carcinoma, Refractory Thyroid Gland Carcinoma, Stage IV Thyroid Gland Follicular Carcinoma AJCC v7.
What interventions are being tested in trial NCT02152995?
The interventions under investigation include: Computed Tomography (PROCEDURE), Laboratory Biomarker Analysis (OTHER), Pharmacodynamic Study (OTHER), Iodine I 124 (OTHER), Iodine I-131 (RADIATION).
Who is sponsoring clinical trial NCT02152995?
This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02152995 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Metastatic Thyroid Gland Carcinoma
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