Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT02148692 · ClinicalTrials.gov registry record · NA
Protective Ventilation With Higher Versus Lower PEEP During General Anesthesia for Surgery in Obese Patients
A NA study, sponsored by Technische Universität Dresden.
- Completed
- Registry status
- NA
- Development phase
- 2,013
- Enrollment target
NCT02148692 is a NA study that has completed, run by Technische Universität Dresden. The registered enrollment target is 2,013 participants.
The verdict
NCT02148692, a NA study, has completed, sponsored by Technische Universität Dresden.
- COMPLETED
- Registry status
- NA
- Development phase
- 2,013 participants
- Enrollment target
Study Summary
Postoperative respiratory failure, particularly after surgery under general anesthesia, adds to the morbidity and mortality of surgical patients. Anesthesiologists inconsistently use positive end-expiratory pressure (PEEP) and recruitment maneuvers in the hope that this may improve oxygenation and protect against postoperative pulmonary complications (PPCs), especially in obese patients. While anesthesiologists tend to use PEEP higher than in non-obese patients. While it is uncertain whether a strategy that uses higher levels of PEEP with recruitment maneuvers truly prevents PPCs in these patients, use of higher levels of PEEP with recruitment maneuvers could compromise intra-operative hemodynamics. The investigators aim to compare a ventilation strategy using higher levels of PEEP with recruitment maneuvers with one using lower levels of PEEP without recruitment maneuvers in obese patients at an intermediate-to-high risk for PPCs. We hypothesize that an intra-operative ventilation strategy using higher levels of PEEP and recruitment maneuvers, as compared to ventilation with lower levels of PEEP without recruitment maneuvers, prevents PPCs in obese patients at an intermediate-to-high risk for PPC.
Interventions
- PROCEDURE Higher PEEP
- PROCEDURE Lower PEEP
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 2,013 participants |
| Start Date | 2014-07 |
| Est. Completion | 2018-05 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02148692
The ClinicalTrials.gov registry entry for NCT02148692 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 2,013 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Technische Universität Dresden, which has 3 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Higher PEEP is the first listed.
NCT02148692 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT02148692 about?
NCT02148692 is a clinical study titled "Protective Ventilation With Higher Versus Lower PEEP During General Anesthesia for Surgery in Obese Patients". Postoperative respiratory failure, particularly after surgery under general anesthesia, adds to the morbidity and mortality of surgical patients. Anesthesiologists inconsistently use positive end-expiratory pressure (PEEP) and recruitment maneuvers in the hope that this may improve oxygenation and p...
What is the current status of trial NCT02148692?
This trial is currently completed. It is a NA study. The enrollment target is 2,013 participants. The study started on 2014-07. Estimated completion is 2018-05.
What interventions are being tested in trial NCT02148692?
The interventions under investigation include: Higher PEEP (PROCEDURE), Lower PEEP (PROCEDURE).
Who is sponsoring clinical trial NCT02148692?
This trial is sponsored by Technische Universität Dresden, which has 3 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
Explore more on PlainTrial
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.