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NCT02148692 · ClinicalTrials.gov registry record · NA
Protective Ventilation With Higher Versus Lower PEEP During General Anesthesia for Surgery in Obese Patients
A NA study, sponsored by Technische Universität Dresden.
- Completed
- Registry status
- NA
- Development phase
- 2,013
- Enrollment target
NCT02148692: Completed NA study, sponsored by Technische Universität Dresden.
NCT02148692 is a NA study that has completed, run by Technische Universität Dresden. The registered enrollment target is 2,013 participants, above the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (43% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02148692, a NA study, has completed, sponsored by Technische Universität Dresden.
- COMPLETED
- Registry status
- NA
- Development phase
- 2,013 participants
- Enrollment target
Study Summary
Postoperative respiratory failure, particularly after surgery under general anesthesia, adds to the morbidity and mortality of surgical patients. Anesthesiologists inconsistently use positive end-expiratory pressure (PEEP) and recruitment maneuvers in the hope that this may improve oxygenation and protect against postoperative pulmonary complications (PPCs), especially in obese patients. While anesthesiologists tend to use PEEP higher than in non-obese patients. While it is uncertain whether a strategy that uses higher levels of PEEP with recruitment maneuvers truly prevents PPCs in these patients, use of higher levels of PEEP with recruitment maneuvers could compromise intra-operative hemodynamics. The investigators aim to compare a ventilation strategy using higher levels of PEEP with recruitment maneuvers with one using lower levels of PEEP without recruitment maneuvers in obese patients at an intermediate-to-high risk for PPCs. We hypothesize that an intra-operative ventilation strategy using higher levels of PEEP and recruitment maneuvers, as compared to ventilation with lower levels of PEEP without recruitment maneuvers, prevents PPCs in obese patients at an intermediate-to-high risk for PPC.
Interventions
- PROCEDURE Higher PEEP
- PROCEDURE Lower PEEP
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 2,013 participants |
| Start Date | 2014-07 |
| Est. Completion | 2018-05 |
| Phase | NA |
What the finished NCT02148692 record still lists
NCT02148692 is an interventional study that assigns participants to a tested intervention. Its 2,013 participants enrollment target places it among the larger protocols in the corpus, above the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (43% higher).
The record links to 0 conditions, and to 2 interventions - of which Higher PEEP is the first listed.
NCT02148692 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02148692 about?
NCT02148692 is a clinical study titled "Protective Ventilation With Higher Versus Lower PEEP During General Anesthesia for Surgery in Obese Patients". Postoperative respiratory failure, particularly after surgery under general anesthesia, adds to the morbidity and mortality of surgical patients. Anesthesiologists inconsistently use positive end-expiratory pressure (PEEP) and recruitment maneuvers in the hope that this may improve oxygenation and p...
What is the current status of trial NCT02148692?
This trial is currently completed. It is a NA study. The enrollment target is 2,013 participants. The study started on 2014-07. Estimated completion is 2018-05.
What interventions are being tested in trial NCT02148692?
The interventions under investigation include: Higher PEEP (PROCEDURE), Lower PEEP (PROCEDURE).
Who is sponsoring clinical trial NCT02148692?
This trial is sponsored by Technische Universität Dresden, which has 3 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02148692's enrollment target sits among peer trials
2,013 52nd of 2000 higher than 1,949 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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