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NCT02080260 · ClinicalTrials.gov registry record · Phase 2

A Study of Regorafenib in Advanced Pancreatic Cancer Patients

A Phase 2 study, sponsored by Wake Forest University Health Sciences.

Completed
Registry status
Phase 2
Development phase
20
Enrollment target

NCT02080260: Completed Phase 2 study, sponsored by Wake Forest University Health Sciences.

NCT02080260 is a Phase 2 study that has completed, run by Wake Forest University Health Sciences. The registered enrollment target is 20 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (85% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02080260, a Phase 2 study, has completed, sponsored by Wake Forest University Health Sciences.

COMPLETED
Registry status
Phase 2
Development phase
20 participants
Enrollment target

Study Summary

This study tests regorafenib as a single agent in the treatment of metastatic pancreatic cancer patients who have progressed after prior chemotherapy with gemcitabine. The prognosis for these patients is particularly grim, no other standard treatment options exist, and novel approaches are desperately needed.

Primary Outcome

16-week progression free survival was determined for each subject as a binary variable indicating whether or not the subject is alive and progression free at 16 weeks after treatment start, with progression defined radiographically using RECIST v1.1 or clinically based upon investigator assessment.

Interventions

  • DRUG regorafenib

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2014-06-06
Est. Completion 2017-06-28
Phase Phase 2
Wake Forest University Health Sciences

1,140 total trials

What the finished NCT02080260 record still lists

NCT02080260 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (85% lower).

The record links to 0 conditions, and to 1 intervention - of which regorafenib is the first listed.

NCT02080260 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02080260 about?

NCT02080260 is a clinical study titled "A Study of Regorafenib in Advanced Pancreatic Cancer Patients". This study tests regorafenib as a single agent in the treatment of metastatic pancreatic cancer patients who have progressed after prior chemotherapy with gemcitabine. The prognosis for these patients is particularly grim, no other standard treatment options exist, and novel approaches are desperate...

What is the current status of trial NCT02080260?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 20 participants. The study started on 2014-06-06. Estimated completion is 2017-06-28.

What interventions are being tested in trial NCT02080260?

The interventions under investigation include: regorafenib (DRUG).

Who is sponsoring clinical trial NCT02080260?

This trial is sponsored by Wake Forest University Health Sciences, which has 1,140 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02080260's enrollment target sits among peer trials

20 1805th of 2000 higher than 107 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02080260, the US trial registry maintained by the National Library of Medicine. NCT02080260 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.