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NCT02077959 · ClinicalTrials.gov registry record · Phase 1

Lenalidomide and Pidilizumab in Treating Patients With Relapsed or Refractory Multiple Myeloma

A Phase 1 study, sponsored by Ohio State University Comprehensive Cancer Center.

Terminated
Registry status
Phase 1
Development phase
20
Enrollment target

NCT02077959: Clinical Trial Phase 1 study, sponsored by Ohio State University Comprehensive Cancer Center.

NCT02077959 is a Phase 1 study that was terminated before completion, run by Ohio State University Comprehensive Cancer Center. The registered enrollment target is 20 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (67% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02077959, a Phase 1 study, was terminated before completion, sponsored by Ohio State University Comprehensive Cancer Center.

TERMINATED
Registry status
Phase 1
Development phase
20 participants
Enrollment target

Study Summary

This phase I/II trial studies the side effects and best dose of lenalidomide and pidilizumab and to see how well they work in treating patients with multiple myeloma that has come back (relapsed) or has not responded to treatment (refractory). Biological therapies, such as lenalidomide, may stimulate the immune system in different ways and stop cancer cells from growing. Monoclonal antibodies, such as pidilizumab, can block cancer growth by blocking the ability of cancer to grow and spread. Giving lenalidomide with pidilizumab may work better in treating relapsed or refractory multiple myeloma.

Interventions

  • OTHER laboratory biomarker analysis
  • DRUG lenalidomide
  • OTHER pharmacological study
  • BIOLOGICAL pidilizumab

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2014-03-03
Est. Completion 2019-05-24
Phase Phase 1

Why NCT02077959 stopped before completion

NCT02077959 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (67% lower).

The record links to 0 conditions, and to 4 interventions - of which laboratory biomarker analysis is the first listed.

NCT02077959 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02077959 about?

NCT02077959 is a clinical study titled "Lenalidomide and Pidilizumab in Treating Patients With Relapsed or Refractory Multiple Myeloma". This phase I/II trial studies the side effects and best dose of lenalidomide and pidilizumab and to see how well they work in treating patients with multiple myeloma that has come back (relapsed) or has not responded to treatment (refractory). Biological therapies, such as lenalidomide, may stimulat...

What is the current status of trial NCT02077959?

This trial is currently terminated. It is a Phase 1 study. The enrollment target is 20 participants. The study started on 2014-03-03. Estimated completion is 2019-05-24.

What interventions are being tested in trial NCT02077959?

The interventions under investigation include: laboratory biomarker analysis (OTHER), lenalidomide (DRUG), pharmacological study (OTHER), pidilizumab (BIOLOGICAL).

Who is sponsoring clinical trial NCT02077959?

This trial is sponsored by Ohio State University Comprehensive Cancer Center, which has 341 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02077959's enrollment target sits among peer trials

20 1629th of 2000 higher than 285 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02077959, the US trial registry maintained by the National Library of Medicine. NCT02077959 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.