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NCT02076321 · ClinicalTrials.gov registry record · Phase 4
The Effect of NSAID Use in the Acute Phase of Skeletally Immature Bone Healing: A Prospective Study
A Phase 4 study, sponsored by University of Missouri-Columbia.
- Completed
- Registry status
- Phase 4
- Development phase
- 102
- Enrollment target
NCT02076321: Completed Phase 4 study, sponsored by University of Missouri-Columbia.
NCT02076321 is a Phase 4 study that has completed, run by University of Missouri-Columbia. The registered enrollment target is 102 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (80% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02076321, a Phase 4 study, has completed, sponsored by University of Missouri-Columbia.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 102 participants
- Enrollment target
Study Summary
Non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen, are excellent medications for providing pain control in children with fractures or those who have surgery to correct bony deformity requiring the bone to be cut (osteotomy) and realigned. There is some data to suggest that these types of medications can adversely affect bone healing in adult patients with broken bones or those having spine fusion surgery. There is little data with regard to how these medications effect bone healing in children. With this project, the investigators' goal is to determine if NSAIDs delay or otherwise adversely effect bone healing and to demonstrate that these medications adequately control pain in children with broken bones or those who have had an osteotomy.
Interventions
- DRUG Acetaminophen
- DRUG Ibuprofen
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 102 participants |
| Start Date | 2014-01 |
| Est. Completion | 2016-11 |
| Phase | Phase 4 |
What the finished NCT02076321 record still lists
NCT02076321 is an interventional study that assigns participants to a tested intervention. The registered 102 participants enrollment target is mid-sized for trials with a published cap, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (80% lower).
The record links to 0 conditions, and to 2 interventions - of which Acetaminophen is the first listed.
NCT02076321 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02076321 about?
NCT02076321 is a clinical study titled "The Effect of NSAID Use in the Acute Phase of Skeletally Immature Bone Healing: A Prospective Study". Non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen, are excellent medications for providing pain control in children with fractures or those who have surgery to correct bony deformity requiring the bone to be cut (osteotomy) and realigned. There is some data to suggest that these type...
What is the current status of trial NCT02076321?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 102 participants. The study started on 2014-01. Estimated completion is 2016-11.
What interventions are being tested in trial NCT02076321?
The interventions under investigation include: Acetaminophen (DRUG), Ibuprofen (DRUG).
Who is sponsoring clinical trial NCT02076321?
This trial is sponsored by University of Missouri-Columbia, which has 291 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02076321's enrollment target sits among peer trials
102 764th of 2000 higher than 1,235 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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