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NCT02075047 · ClinicalTrials.gov registry record · Phase 3

Efficacy and Safety Trial of Flexible Doses of Oral Ziprasidone in Children and Adolescents With Bipolar I Disorder

A Phase 3 study, sponsored by Pfizer's Upjohn has merged with Mylan to form Viatris.

Terminated
Registry status
Phase 3
Development phase
171
Enrollment target

NCT02075047: Clinical Trial Phase 3 study, sponsored by Pfizer's Upjohn has merged with Mylan to form Viatris.

NCT02075047 is a Phase 3 study that was terminated before completion, run by Pfizer's Upjohn has merged with Mylan to form Viatris. The registered enrollment target is 171 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (78% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02075047, a Phase 3 study, was terminated before completion, sponsored by Pfizer's Upjohn has merged with Mylan to form Viatris.

TERMINATED
Registry status
Phase 3
Development phase
171 participants
Enrollment target

Study Summary

The purpose of this study is to determine if ziprasidone is safe and effective for the treatment of children and adolescents (ages 10-17) with bipolar I disorder (manic or mixed).

Primary Outcome

YMRS: an 11-item scale that measured the severity of manic episodes. Four items (irritability, speech, thought content, and disruptive/ aggressive behavior) were rated on a scale from 0 (symptom absent) to 8 (symptom extremely severe). The remaining items were rated on a scale from 0 (symptom absent) to 4 (symptom extremely severe). YMRS total score was sum of score of all 11 items and ranged from 0 (no symptoms) to 60 (extreme severity of symptoms), higher score indicated higher severity of man

Interventions

  • DRUG placebo oral capsules
  • DRUG ziprasidone oral capsules

Trial Details

FieldValue
Enrollment Target 171 participants
Start Date 2014-05-23
Est. Completion 2020-05-18
Phase Phase 3

Why NCT02075047 stopped before completion

NCT02075047 is an interventional study that assigns participants to a tested intervention. The registered 171 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (78% lower).

The record links to 0 conditions, and to 2 interventions - of which placebo oral capsules is the first listed.

NCT02075047 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02075047 about?

NCT02075047 is a clinical study titled "Efficacy and Safety Trial of Flexible Doses of Oral Ziprasidone in Children and Adolescents With Bipolar I Disorder". The purpose of this study is to determine if ziprasidone is safe and effective for the treatment of children and adolescents (ages 10-17) with bipolar I disorder (manic or mixed).

What is the current status of trial NCT02075047?

This trial is currently terminated. It is a Phase 3 study. The enrollment target is 171 participants. The study started on 2014-05-23. Estimated completion is 2020-05-18.

What interventions are being tested in trial NCT02075047?

The interventions under investigation include: placebo oral capsules (DRUG), ziprasidone oral capsules (DRUG).

Who is sponsoring clinical trial NCT02075047?

This trial is sponsored by Pfizer's Upjohn has merged with Mylan to form Viatris, which has 158 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02075047's enrollment target sits among peer trials

171 1451st of 2000 higher than 548 of 2,000 other Phase 3 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02075047, the US trial registry maintained by the National Library of Medicine. NCT02075047 (mid enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.