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NCT02066909 · ClinicalTrials.gov registry record · Phase 1

A Study To Observe Safety And Blood Concentrations Of PF-06649751 During And Following The Oral Administration Of Multiple Doses Of PF-06649751 In Healthy Adult Western and Japanese Volunteers

A Phase 1 study of Healthy, sponsored by Pfizer.

Completed
Registry status
Phase 1
Development phase
77
Enrollment target
1
Study location

NCT02066909: Completed Phase 1 study of Healthy, sponsored by Pfizer.

NCT02066909 is a Phase 1 study of Healthy that has completed, run by Pfizer. The registered enrollment target is 77 participants, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (88% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02066909, a Phase 1 study of Healthy, has completed, sponsored by Pfizer.

COMPLETED
Registry status
Phase 1
Development phase
77 participants
Enrollment target
1
Study location

Study Summary

This study is designed to evaluate the safety and plasma concentrations of PF-06649751 in healthy volunteers following one or two times daily oral dosing of PF-06649751 for 14 days (Cohorts 1 - 4), 21 days (Cohort 5), or 28 days (Cohorts 6 - 8). Cohort 9 will dose Japanese healthy volunteers in a manner identical to Cohort 4 and is intended to bridge the safety/tolerability and PK data from the Western and Japanese populations.

Primary Outcome

Measurement of blood pressure and pulse rate

Conditions Studied

Interventions

  • DRUG 0.15 mg PF-06649751
  • DRUG 0.5 mg PF-06649751
  • DRUG 1.5 mg PF-06649751
  • DRUG 1.5 mg PF-06649751 21 Days

Study Locations (1)

Connecticut

  • New Haven Clinical Research Unit - New Haven

Trial Details

FieldValue
Enrollment Target 77 participants
Start Date 2014-02
Est. Completion 2015-04
Phase Phase 1
Pfizer

1,845 total trials

What the finished NCT02066909 record still lists

NCT02066909 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 77 participants, a relatively small participant target, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (88% lower).

The record links to 1 condition, with Healthy appearing as the primary indexed condition, and to 4 interventions - of which 0.15 mg PF-06649751 is the first listed.

NCT02066909 reports a single indexed study location in Connecticut.

Frequently Asked Questions

What is clinical trial NCT02066909 about?

NCT02066909 is a clinical study titled "A Study To Observe Safety And Blood Concentrations Of PF-06649751 During And Following The Oral Administration Of Multiple Doses Of PF-06649751 In Healthy Adult Western and Japanese Volunteers". This study is designed to evaluate the safety and plasma concentrations of PF-06649751 in healthy volunteers following one or two times daily oral dosing of PF-06649751 for 14 days (Cohorts 1 - 4), 21 days (Cohort 5), or 28 days (Cohorts 6 - 8). Cohort 9 will dose Japanese healthy volunteers in a ma...

What is the current status of trial NCT02066909?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 77 participants. The study started on 2014-02. Estimated completion is 2015-04.

What conditions does trial NCT02066909 study?

This clinical trial studies the following conditions: Healthy.

What interventions are being tested in trial NCT02066909?

The interventions under investigation include: 0.15 mg PF-06649751 (DRUG), 0.5 mg PF-06649751 (DRUG), 1.5 mg PF-06649751 (DRUG), 1.5 mg PF-06649751 21 Days (DRUG).

Who is sponsoring clinical trial NCT02066909?

This trial is sponsored by Pfizer, which has 1,845 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02066909 being conducted?

This trial has 1 study location across Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Healthy

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT02066909's enrollment target sits among peer trials

77 291st of 1090 higher than 797 of 1,090 other Healthy trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Healthy trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02066909, the US trial registry maintained by the National Library of Medicine. NCT02066909 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.