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NCT02059343 · ClinicalTrials.gov registry record
Pharmacokinetics of Dexmedetomidine in Children During Cardiopulmonary Bypass (CPB)
A clinical trial, sponsored by Duke University.
- Completed
- Registry status
- 18
- Enrollment target
NCT02059343: Completed study, sponsored by Duke University.
NCT02059343 is a clinical trial that has completed, run by Duke University. The registered enrollment target is 18 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02059343 has completed, sponsored by Duke University.
- COMPLETED
- Registry status
- 18 participants
- Enrollment target
Study Summary
Dexmedetomidine is increasingly used for sedation in children placed on cardiopulmonary bypass for heart surgery. It is also often used after surgery and may be particularly helpful for children with heart disease. In order for this medication to be helpful and to minimize risks associated with taking the medication, it is important to provide correct dosing for this medication. Based on evidence from studies of other medications used during heart surgery, it is likely that dosing of dexmedetomidine while on cardiopulmonary bypass is different from dosing in other settings. The purpose of this study is to evaluate how the heart-lung bypass machine affects dexmedetomidine levels in the body.
Primary Outcome
The plasma pharmacokinetics of dexmedetomidine will include * Clearance (CL) * Volume of distribution (V) * Area under the curve (AUC) * Oxygenator extraction efficiency
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 18 participants |
| Start Date | 2014-03 |
| Est. Completion | 2014-11 |
What the finished NCT02059343 record still lists
NCT02059343 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 18 participants, a relatively small participant target.
The record links to 0 conditions, and to 0 interventions.
NCT02059343 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02059343 about?
NCT02059343 is a clinical study titled "Pharmacokinetics of Dexmedetomidine in Children During Cardiopulmonary Bypass (CPB)". Dexmedetomidine is increasingly used for sedation in children placed on cardiopulmonary bypass for heart surgery. It is also often used after surgery and may be particularly helpful for children with heart disease. In order for this medication to be helpful and to minimize risks associated with taki...
What is the current status of trial NCT02059343?
This trial is currently completed. The enrollment target is 18 participants. The study started on 2014-03. Estimated completion is 2014-11.
Who is sponsoring clinical trial NCT02059343?
This trial is sponsored by Duke University, which has 1,725 total clinical trials registered on ClinicalTrials.gov.
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