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Study to Evaluate the Efficacy and Safety of MEDI9929 (AMG 157) in Adult Subjects With Inadequately Controlled, Severe Asthma
NCT02054130 · View on ClinicalTrials.gov ↗
Study Summary
The primary objective of the study is to evaluate the effect of 3 dose levels of MEDI9929 (AMG 157) on asthma exacerbations in adult subjects with inadequately controlled, severe asthma.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG MEDI9929 70 mg
- DRUG MEDI9929 210 mg
- DRUG MEDI9929 280 mg
Study Locations (20)
California
- Research Site — Los Angeles
- Research Site — Los Angeles
Florida
- Research Site — Miami
- Research Site — Oviedo
New York
- Research Site — New York
- Research Site — New York
North Carolina
- Research Site — Charlotte
- Research Site — Charlotte
South Carolina
- Research Site — Rock Hill
- Research Site — Spartanburg
Other
- Research Site — Plovdiv
- Research Site — Sofia
Georgia
- Research Site — Savannah
Illinois
- Research Site — Peoria
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 584 participants |
| Start Date | 2013-12-13 |
| Est. Completion | 2017-03-01 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02054130
The ClinicalTrials.gov registry entry for NCT02054130 describes a study currently listed as completed. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 584 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is MedImmune, which has 55 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Asthma appearing as the primary indexed condition, and to 4 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT02054130 reports 20 study locations spanning 14 distinct geographic areas — top geographies include California, Florida, New York. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT02054130 about?
NCT02054130 is a clinical study titled "Study to Evaluate the Efficacy and Safety of MEDI9929 (AMG 157) in Adult Subjects With Inadequately Controlled, Severe Asthma". The primary objective of the study is to evaluate the effect of 3 dose levels of MEDI9929 (AMG 157) on asthma exacerbations in adult subjects with inadequately controlled, severe asthma.
What is the current status of trial NCT02054130?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 584 participants. The study started on 2013-12-13. Estimated completion is 2017-03-01.
What conditions does trial NCT02054130 study?
This clinical trial studies the following conditions: Asthma. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT02054130?
The interventions under investigation include: Placebo (DRUG), MEDI9929 70 mg (DRUG), MEDI9929 210 mg (DRUG), MEDI9929 280 mg (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT02054130?
This trial is sponsored by MedImmune, which has 55 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT02054130 being conducted?
This trial has 20 study locations across California, Florida, Georgia, Illinois, Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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