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NCT02052479 · ClinicalTrials.gov registry record · NA
Insulin Differences Between African-American and Caucasian Female Adolescents With Polycystic Ovary Syndrome (PCOS)
A NA study, sponsored by Nationwide Children's Hospital.
- Terminated
- Registry status
- NA
- Development phase
- 12
- Enrollment target
NCT02052479 is a NA study that was terminated before completion, run by Nationwide Children's Hospital. The registered enrollment target is 12 participants.
The verdict
NCT02052479, a NA study, was terminated before completion, sponsored by Nationwide Children's Hospital.
- TERMINATED
- Registry status
- NA
- Development phase
- 12 participants
- Enrollment target
Study Summary
The purpose of this research study is to see if there are differences between African-American and Caucasian girls with Polycystic Ovary Syndrome (PCOS) in how their bodies respond to a type of sugar, called glucose, the body's main source of energy. PCOS is one of the most common endocrine disorders among females. Features can include anovulation (eggs are not released from the ovaries) resulting in irregular menstrual periods, excessive amounts of androgenic (male) hormones resulting in acne and hirsutism (excessive hair growth on the face and body), and polycystic ovaries (small sac-like structures \[cysts\] on your ovaries) seen on ultrasound. Girls with PCOS also have higher levels of insulin in their bodies (called hyperinsulinism) but are not able to use insulin very well (called insulin resistance) resulting in an increased risk of diabetes. Diabetes is when you have high levels of glucose (sugar) in your blood. Many studies have looked at how bodies respond to glucose and have shown that compared to Caucasians, healthy African-Americans produce much more insulin (hyperinsulinism) but are not able to use it as well (insulin resistance) in childhood, adolescence, and adulthood. Insulin is a hormone that helps glucose move from the blood into the muscles for the body to use as energy. PCOS is associated with increased levels of insulin (hyperinsulinism) and not being able to use it as well (insulin resistance). So we want to see if there is a difference in insulin production (secretion) and insulin resistance between African-Americans and Caucasians girls with PCOS. To do this, we will look at blood glucose and insulin levels in response to giving glucose in African-American and Caucasian girls who have PCOS. The results of this study may ultimately help to more effectively target treatment therapy in individuals with PCOS that have increased insulin secretion and/or increased insulin resistance.
Interventions
- OTHER Frequently Sampled Intravenous Glucose Tolerance Test (FSIVGTT)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 12 participants |
| Start Date | 2014-01 |
| Est. Completion | 2015-06 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02052479
The ClinicalTrials.gov registry entry for NCT02052479 describes a study currently listed as terminated, categorized as NA. The registered enrollment target is 12 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Nationwide Children's Hospital, which has 188 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which Frequently Sampled Intravenous Glucose Tolerance Test (FSIVGTT) is the first listed.
NCT02052479 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT02052479 about?
NCT02052479 is a clinical study titled "Insulin Differences Between African-American and Caucasian Female Adolescents With Polycystic Ovary Syndrome (PCOS)". The purpose of this research study is to see if there are differences between African-American and Caucasian girls with Polycystic Ovary Syndrome (PCOS) in how their bodies respond to a type of sugar, called glucose, the body's main source of energy. PCOS is one of the most common endocrine disorder...
What is the current status of trial NCT02052479?
This trial is currently terminated. It is a NA study. The enrollment target is 12 participants. The study started on 2014-01. Estimated completion is 2015-06.
What interventions are being tested in trial NCT02052479?
The interventions under investigation include: Frequently Sampled Intravenous Glucose Tolerance Test (FSIVGTT) (OTHER).
Who is sponsoring clinical trial NCT02052479?
This trial is sponsored by Nationwide Children's Hospital, which has 188 total clinical trials registered on ClinicalTrials.gov.
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