Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT02049307 · ClinicalTrials.gov registry record · Phase 2
Losartan to Reduce Inflammation and Fibrosis Endpoints in HIV Trial
A Phase 2 study, sponsored by Hennepin Healthcare Research Institute.
- Completed
- Registry status
- Phase 2
- Development phase
- 108
- Enrollment target
NCT02049307: Completed Phase 2 study, sponsored by Hennepin Healthcare Research Institute.
NCT02049307 is a Phase 2 study that has completed, run by Hennepin Healthcare Research Institute. The registered enrollment target is 108 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (19% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02049307, a Phase 2 study, has completed, sponsored by Hennepin Healthcare Research Institute.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 108 participants
- Enrollment target
Study Summary
The purpose of this study is to evaluate the potential effectiveness of losartan (100mg daily) for reducing inflammation and improving immune recovery.
Primary Outcome
Difference between treatment and control IL-6 plasma levels from pre-treatment to on-treatment values
Interventions
- DRUG Matching placebo
- DRUG Losartan 100mg daily
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 108 participants |
| Start Date | 2014-10-16 |
| Est. Completion | 2018-12-14 |
| Phase | Phase 2 |
What the finished NCT02049307 record still lists
NCT02049307 is an interventional study that assigns participants to a tested intervention. The registered 108 participants enrollment target is mid-sized for trials with a published cap, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (19% lower).
The record links to 0 conditions, and to 2 interventions - of which Matching placebo is the first listed.
NCT02049307 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02049307 about?
NCT02049307 is a clinical study titled "Losartan to Reduce Inflammation and Fibrosis Endpoints in HIV Trial". The purpose of this study is to evaluate the potential effectiveness of losartan (100mg daily) for reducing inflammation and improving immune recovery.
What is the current status of trial NCT02049307?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 108 participants. The study started on 2014-10-16. Estimated completion is 2018-12-14.
What interventions are being tested in trial NCT02049307?
The interventions under investigation include: Matching placebo (DRUG), Losartan 100mg daily (DRUG).
Who is sponsoring clinical trial NCT02049307?
This trial is sponsored by Hennepin Healthcare Research Institute, which has 63 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02049307's enrollment target sits among peer trials
108 640th of 2000 higher than 1,355 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT02703207 · 108 participants · NA
Neurocognitive and Health Impact of Sleep Apnea in Elderly Veterans With Comorbid COPD
- NCT02744677 · 108 participants · NA
COMPASSION S3 - Evaluation of the SAPIEN 3 Transcatheter Heart Valve in Patients With Pulmonary Valve Dysfunction
- NCT02781883 · 108 participants · Phase 2
Clinical Trial of BP1001 in Combination With With Venetoclax Plus Decitabine in AML
- NCT03848663 · 108 participants · NA
Visual Remapping to Aid Reading With Field Loss
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI