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NCT02046187 · ClinicalTrials.gov registry record · Phase 1
Ketogenic Diet With Radiation and Chemotherapy for Newly Diagnosed Glioblastoma
A Phase 1 study, sponsored by St. Joseph's Hospital and Medical Center, Phoenix.
- Terminated
- Registry status
- Phase 1
- Development phase
- 14
- Enrollment target
NCT02046187: Clinical Trial Phase 1 study, sponsored by St. Joseph's Hospital and Medical Center, Phoenix.
NCT02046187 is a Phase 1 study that was terminated before completion, run by St. Joseph's Hospital and Medical Center, Phoenix. The registered enrollment target is 14 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (77% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02046187, a Phase 1 study, was terminated before completion, sponsored by St. Joseph's Hospital and Medical Center, Phoenix.
- TERMINATED
- Registry status
- Phase 1
- Development phase
- 14 participants
- Enrollment target
Study Summary
This study aims to see if reducing blood sugar and increasing ketones (a metabolic product that comes from using fats for energy) can increase survival and enhance the the effects of standard radiation and chemotherapy treatments used to treat glioblastoma multiforme (GBM). These changes occur from use of a ketogenic diet. This research has 2 goals: 1. Show that patients can tolerate the diet and maintain low blood glucose and high blood ketone levels. 2. Show if this diet enhances the effectiveness of standard treatment by prolonging survival of patients with a GBM.
Primary Outcome
Number of participants with adverse events from initiation of ketogenic diet through end of radiation (while on ketogenic diet)
Interventions
- DRUG Temozolomide
- RADIATION Radiation therapy
- DIETARY_SUPPLEMENT Ketogenic Diet
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 14 participants |
| Start Date | 2013-10 |
| Est. Completion | 2017-02 |
| Phase | Phase 1 |
Why NCT02046187 stopped before completion
NCT02046187 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 14 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (77% lower).
The record links to 0 conditions, and to 3 interventions - of which Temozolomide is the first listed.
NCT02046187 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02046187 about?
NCT02046187 is a clinical study titled "Ketogenic Diet With Radiation and Chemotherapy for Newly Diagnosed Glioblastoma". This study aims to see if reducing blood sugar and increasing ketones (a metabolic product that comes from using fats for energy) can increase survival and enhance the the effects of standard radiation and chemotherapy treatments used to treat glioblastoma multiforme (GBM). These changes occur from ...
What is the current status of trial NCT02046187?
This trial is currently terminated. It is a Phase 1 study. The enrollment target is 14 participants. The study started on 2013-10. Estimated completion is 2017-02.
What interventions are being tested in trial NCT02046187?
The interventions under investigation include: Temozolomide (DRUG), Radiation therapy (RADIATION), Ketogenic Diet (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT02046187?
This trial is sponsored by St. Joseph's Hospital and Medical Center, Phoenix, which has 44 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02046187's enrollment target sits among peer trials
14 1844th of 2000 higher than 154 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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