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NCT02039700 · ClinicalTrials.gov registry record · Phase 1
Bioavailability of Lesinurad and Intravenous [14C]Lesinurad
A Phase 1 study of Healthy, sponsored by Ardea Biosciences.
- Completed
- Registry status
- Phase 1
- Development phase
- 10
- Enrollment target
- 1
- Study location
NCT02039700: Completed Phase 1 study of Healthy, sponsored by Ardea Biosciences.
NCT02039700 is a Phase 1 study of Healthy that has completed, run by Ardea Biosciences. The registered enrollment target is 10 participants, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02039700, a Phase 1 study of Healthy, has completed, sponsored by Ardea Biosciences.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 10 participants
- Enrollment target
- 1
- Study location
Study Summary
This study will assess the absolute bioavailability of a single oral dose of lesinurad and evaluate the pharmacokinetic (PK) parameters of lesinurad and \[14C\]lesinurad in healthy adult male subjects.
Primary Outcome
PK profile in terms of maximum observed concentration (Cmax), time of occurrence of maximum observed concentration (Tmax), area under the concentration-time curve (AUC), apparent terminal half-life (t½), mean residence time (MRT), mean absorption time (MAT), and absolute bioavailability (F).
Conditions Studied
Interventions
- DRUG Lesinurad 400 mg
- DRUG [14C]lesinurad (100 μg per 10 mL)
Study Locations (1)
Wisconsin
- - Madison
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10 participants |
| Start Date | 2014-01 |
| Est. Completion | 2014-04 |
| Phase | Phase 1 |
What the finished NCT02039700 record still lists
NCT02039700 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (98% lower).
The record links to 1 condition, with Healthy appearing as the primary indexed condition, and to 2 interventions - of which Lesinurad 400 mg is the first listed.
NCT02039700 reports a single indexed study location in Wisconsin.
Frequently Asked Questions
What is clinical trial NCT02039700 about?
NCT02039700 is a clinical study titled "Bioavailability of Lesinurad and Intravenous [14C]Lesinurad". This study will assess the absolute bioavailability of a single oral dose of lesinurad and evaluate the pharmacokinetic (PK) parameters of lesinurad and \[14C\]lesinurad in healthy adult male subjects.
What is the current status of trial NCT02039700?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 10 participants. The study started on 2014-01. Estimated completion is 2014-04.
What conditions does trial NCT02039700 study?
This clinical trial studies the following conditions: Healthy.
What interventions are being tested in trial NCT02039700?
The interventions under investigation include: Lesinurad 400 mg (DRUG), [14C]lesinurad (100 μg per 10 mL) (DRUG).
Who is sponsoring clinical trial NCT02039700?
This trial is sponsored by Ardea Biosciences, which has 32 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02039700 being conducted?
This trial has 1 study location across Wisconsin. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Healthy
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT02039700's enrollment target sits among peer trials
10 1035th of 1090 higher than 35 of 1,090 other Healthy trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Healthy trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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