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MRI Study of Changes in Blood-Brain/Tumor-Barrier Permeability in Patients With Brain Metastases During and After Radiotherapy

NCT02031237 · View on ClinicalTrials.gov ↗

Study Summary

This study aims to assess changes in vascular permeability in the brain tumor, and in the surrounding brain, due to radiation therapy, using Magnetic Resonance Imaging (MRI).

Conditions Studied

Interventions

  • RADIATION Fractionated Stereotactic Radiation Therapy (FSRT)
  • RADIATION Single Fraction Stereotactic Radiosurgery (SRS)
  • RADIATION Fractionated Whole Brain Radiation Therapy (WBRT)
  • DEVICE Magnetic Resonance Imaging (MRI) Assessments

Study Locations (1)

Michigan

  • University of Michigan Hospital — Ann Arbor

Trial Details

FieldValue
Enrollment Target 52 participants
Start Date 2005-04
Est. Completion 2014-12

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT02031237

The ClinicalTrials.gov registry entry for NCT02031237 describes a study currently listed as completed. It is categorized as an unspecified phase, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 52 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Michigan Rogel Cancer Center, which has 261 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Brain Metastases appearing as the primary indexed condition, and to 4 interventions — of which Fractionated Stereotactic Radiation Therapy (FSRT) is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT02031237 reports 1 study location spanning 1 distinct geographic area — top geographies include Michigan. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT02031237 about?

NCT02031237 is a clinical study titled "MRI Study of Changes in Blood-Brain/Tumor-Barrier Permeability in Patients With Brain Metastases During and After Radiotherapy". This study aims to assess changes in vascular permeability in the brain tumor, and in the surrounding brain, due to radiation therapy, using Magnetic Resonance Imaging (MRI).

What is the current status of trial NCT02031237?

This trial is currently completed. The enrollment target is 52 participants. The study started on 2005-04. Estimated completion is 2014-12.

What conditions does trial NCT02031237 study?

This clinical trial studies the following conditions: Brain Metastases. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT02031237?

The interventions under investigation include: Fractionated Stereotactic Radiation Therapy (FSRT) (RADIATION), Single Fraction Stereotactic Radiosurgery (SRS) (RADIATION), Fractionated Whole Brain Radiation Therapy (WBRT) (RADIATION), Magnetic Resonance Imaging (MRI) Assessments (DEVICE). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT02031237?

This trial is sponsored by University of Michigan Rogel Cancer Center, which has 261 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT02031237 being conducted?

This trial has 1 study location across Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial