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NCT02014415 · ClinicalTrials.gov registry record
Alpha-1 Antitrypsin Deficiency Adult Liver Study
A clinical trial of Alpha-1 Antitrypsin Deficiency, sponsored by St. Louis University.
- Active
- Registry status
- 120
- Enrollment target
- 3
- Study locations
NCT02014415: Active study of Alpha-1 Antitrypsin Deficiency, sponsored by St. Louis University.
NCT02014415 is a study of Alpha-1 Antitrypsin Deficiency that is active but no longer recruiting, run by St. Louis University. The registered enrollment target is 120 participants, below the 2,337-participant average among 24 other Alpha-1 Antitrypsin Deficiency trials with a reported enrollment target (95% lower). The trial reports 3 study locations across 3 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02014415, a study of Alpha-1 Antitrypsin Deficiency, is active but no longer recruiting, sponsored by St. Louis University.
- ACTIVE NOT RECRUITING
- Registry status
- 120 participants
- Enrollment target
- 3
- Study locations
Study Summary
The investigators hypothesize that there is liver injury (inflammation, fibrosis, cirrhosis) in adults with Alpha-1 Antitrypsin Deficiency (AATD), which is asymptomatic, under-recognized, and undiagnosed. In addition, the investigators believe that the genetic and environmental factors that play an important role in the development of alpha-1 antitrypsin (AAT) liver disease, can be identified by comparing a cohort database of clinical disease information to linked biospecimen and DNA samples.
Conditions Studied
Interventions
- PROCEDURE Liver Biopsy (Biopsy Group Only)
Study Locations (3)
California
- University of California - San Diego
Massachusetts
- Boston University School of Medicine - Boston
Missouri
- Saint Louis University - St Louis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 120 participants |
| Start Date | 2013-12 |
| Est. Completion | 2026-07 |
What the registry record for NCT02014415 still lists
NCT02014415 is an observational study that tracks outcomes without assigning an intervention. The registered 120 participants enrollment target is mid-sized for trials with a published cap, below the 2,337-participant average among 24 other Alpha-1 Antitrypsin Deficiency trials with a reported enrollment target (95% lower).
The record links to 1 condition, with Alpha-1 Antitrypsin Deficiency appearing as the primary indexed condition, and to 1 intervention - of which Liver Biopsy (Biopsy Group Only) is the first listed.
NCT02014415 reports a single indexed study location in California, Massachusetts, Missouri.
Frequently Asked Questions
What is clinical trial NCT02014415 about?
NCT02014415 is a clinical study titled "Alpha-1 Antitrypsin Deficiency Adult Liver Study". The investigators hypothesize that there is liver injury (inflammation, fibrosis, cirrhosis) in adults with Alpha-1 Antitrypsin Deficiency (AATD), which is asymptomatic, under-recognized, and undiagnosed. In addition, the investigators believe that the genetic and environmental factors that play an ...
What is the current status of trial NCT02014415?
This trial is currently active not recruiting. The enrollment target is 120 participants. The study started on 2013-12. Estimated completion is 2026-07.
What conditions does trial NCT02014415 study?
This clinical trial studies the following conditions: Alpha-1 Antitrypsin Deficiency.
What interventions are being tested in trial NCT02014415?
The interventions under investigation include: Liver Biopsy (Biopsy Group Only) (PROCEDURE).
Who is sponsoring clinical trial NCT02014415?
This trial is sponsored by St. Louis University, which has 107 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02014415 being conducted?
This trial has 3 study locations across California, Massachusetts, Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Alpha-1 Antitrypsin Deficiency
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Where NCT02014415's enrollment target sits among peer trials
120 8th of 24 higher than 17 of 24 other Alpha-1 Antitrypsin Deficiency trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Alpha-1 Antitrypsin Deficiency trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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