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NCT02014415 · ClinicalTrials.gov registry record

Alpha-1 Antitrypsin Deficiency Adult Liver Study

A clinical trial of Alpha-1 Antitrypsin Deficiency, sponsored by St. Louis University.

Active
Registry status
120
Enrollment target
3
Study locations

NCT02014415 is a study of Alpha-1 Antitrypsin Deficiency that is active but no longer recruiting, run by St. Louis University. The registered enrollment target is 120 participants, below the 3,071-participant average among 18 other Alpha-1 Antitrypsin Deficiency trials with a reported enrollment target (96% lower). The trial reports 3 study locations across 3 states.

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The verdict

NCT02014415, a study of Alpha-1 Antitrypsin Deficiency, is active but no longer recruiting, sponsored by St. Louis University.

ACTIVE NOT RECRUITING
Registry status
120 participants
Enrollment target
3
Study locations

Study Summary

The investigators hypothesize that there is liver injury (inflammation, fibrosis, cirrhosis) in adults with Alpha-1 Antitrypsin Deficiency (AATD), which is asymptomatic, under-recognized, and undiagnosed. In addition, the investigators believe that the genetic and environmental factors that play an important role in the development of alpha-1 antitrypsin (AAT) liver disease, can be identified by comparing a cohort database of clinical disease information to linked biospecimen and DNA samples.

Conditions Studied

Alpha-1 Antitrypsin Deficiency

Interventions

  • PROCEDURE Liver Biopsy (Biopsy Group Only)

Study Locations (3)

California

  • University of California - San Diego

Massachusetts

  • Boston University School of Medicine - Boston

Missouri

  • Saint Louis University - St Louis

Trial Details

FieldValue
Enrollment Target 120 participants
Start Date 2013-12
Est. Completion 2026-07

Sponsor

St. Louis University

107 total trials

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What the Registry Record Tells You About NCT02014415

The ClinicalTrials.gov registry entry for NCT02014415 describes a study currently listed as active not recruiting, categorized as an unspecified phase. The registered enrollment target is 120 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 3,071-participant average among 18 other Alpha-1 Antitrypsin Deficiency trials with a reported enrollment target (96% lower). The listed sponsor is St. Louis University, which has 107 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Alpha-1 Antitrypsin Deficiency appearing as the primary indexed condition, and to 1 intervention - of which Liver Biopsy (Biopsy Group Only) is the first listed.

NCT02014415 reports 3 study locations spanning 3 distinct geographic areas - top geographies include California, Massachusetts, Missouri.

Frequently Asked Questions

What is clinical trial NCT02014415 about?

NCT02014415 is a clinical study titled "Alpha-1 Antitrypsin Deficiency Adult Liver Study". The investigators hypothesize that there is liver injury (inflammation, fibrosis, cirrhosis) in adults with Alpha-1 Antitrypsin Deficiency (AATD), which is asymptomatic, under-recognized, and undiagnosed. In addition, the investigators believe that the genetic and environmental factors that play an ...

What is the current status of trial NCT02014415?

This trial is currently active not recruiting. The enrollment target is 120 participants. The study started on 2013-12. Estimated completion is 2026-07.

What conditions does trial NCT02014415 study?

This clinical trial studies the following conditions: Alpha-1 Antitrypsin Deficiency.

What interventions are being tested in trial NCT02014415?

The interventions under investigation include: Liver Biopsy (Biopsy Group Only) (PROCEDURE).

Who is sponsoring clinical trial NCT02014415?

This trial is sponsored by St. Louis University, which has 107 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02014415 being conducted?

This trial has 3 study locations across California, Massachusetts, Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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