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NCT02005601 · ClinicalTrials.gov registry record · Phase 4
Does Duloxetine Reduce Sub-Acute Pain After Knee Arthroplasty?
A Phase 4 study of Total Knee Arthroplasty, sponsored by Hospital for Special Surgery, New York.
- Completed
- Registry status
- Phase 4
- Development phase
- 106
- Enrollment target
- 1
- Study location
NCT02005601: Completed Phase 4 study of Total Knee Arthroplasty, sponsored by Hospital for Special Surgery, New York.
NCT02005601 is a Phase 4 study of Total Knee Arthroplasty that has completed, run by Hospital for Special Surgery, New York. The registered enrollment target is 106 participants, below the 291-participant average among 29 other Total Knee Arthroplasty trials with a reported enrollment target (64% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02005601, a Phase 4 study of Total Knee Arthroplasty, has completed, sponsored by Hospital for Special Surgery, New York.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 106 participants
- Enrollment target
- 1
- Study location
Study Summary
We are investigating the impact of duloxetine ("Cymbalta"), a serotonin and norepinephrine reuptake inhibitor, on pain after total knee arthroplasty (TKA). Specifically, the investigators will determine whether duloxetine, 60 mg daily for 2 weeks, reduces pain scores 2 weeks after TKA.
Primary Outcome
When considering the pain in the knee in which you are having/had surgery, on a scale of 0-10, with 0 being no pain and 10 being pain as bad as you can imagine, how would you describe your level of pain in the last 24 hours during ambulation?
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Duloxetine 60mg
Study Locations (1)
New York
- Hospital for Special Surgery - New York
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 106 participants |
| Start Date | 2013-11 |
| Est. Completion | 2015-08 |
| Phase | Phase 4 |
What the finished NCT02005601 record still lists
NCT02005601 is an interventional study that assigns participants to a tested intervention. The registered 106 participants enrollment target is mid-sized for trials with a published cap, below the 291-participant average among 29 other Total Knee Arthroplasty trials with a reported enrollment target (64% lower).
The record links to 1 condition, with Total Knee Arthroplasty appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT02005601 reports a single indexed study location in New York.
Frequently Asked Questions
What is clinical trial NCT02005601 about?
NCT02005601 is a clinical study titled "Does Duloxetine Reduce Sub-Acute Pain After Knee Arthroplasty?". We are investigating the impact of duloxetine ("Cymbalta"), a serotonin and norepinephrine reuptake inhibitor, on pain after total knee arthroplasty (TKA). Specifically, the investigators will determine whether duloxetine, 60 mg daily for 2 weeks, reduces pain scores 2 weeks after TKA.
What is the current status of trial NCT02005601?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 106 participants. The study started on 2013-11. Estimated completion is 2015-08.
What conditions does trial NCT02005601 study?
This clinical trial studies the following conditions: Total Knee Arthroplasty.
What interventions are being tested in trial NCT02005601?
The interventions under investigation include: Placebo (DRUG), Duloxetine 60mg (DRUG).
Who is sponsoring clinical trial NCT02005601?
This trial is sponsored by Hospital for Special Surgery, New York, which has 194 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02005601 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Total Knee Arthroplasty
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT02005601's enrollment target sits among peer trials
106 17th of 29 higher than 13 of 29 other Total Knee Arthroplasty trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Total Knee Arthroplasty trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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