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NCT01994720 · ClinicalTrials.gov registry record · Phase 3
[SOCRATES -Acute Stroke Or Transient IsChaemic Attack TReated With Aspirin or Ticagrelor and Patient OutcomES]
A Phase 3 study, sponsored by AstraZeneca.
- Completed
- Registry status
- Phase 3
- Development phase
- 13,307
- Enrollment target
NCT01994720: Completed Phase 3 study, sponsored by AstraZeneca.
NCT01994720 is a Phase 3 study that has completed, run by AstraZeneca. The registered enrollment target is 13,307 participants, above the 771-participant average among 15,282 other Phase 3 trials with a reported enrollment target (1626% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01994720, a Phase 3 study, has completed, sponsored by AstraZeneca.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 13,307 participants
- Enrollment target
Study Summary
The primary objective of the study is to compare the effect of 90-day treatment with ticagrelor (180 mg \[two 90 mg tablets\] loading dose on Day 1 followed by 90 mg twice daily maintenance dose for the remainder of the study) vs acetylsalicylic acid (ASA)-aspirin (300 mg \[three 100 mg tablets\] loading dose on Day 1 followed by 100 mg once daily maintenance dose for the remainder of the study) for the prevention of major vascular events (composite of stroke, myocardial infarction \[MI\], and death) in patients with acute ischaemic stroke or transient ischaemic attack (TIA).
Primary Outcome
Participants with stroke, MI or death. If no event, censoring occures at the minimum of (last date of event assessment, end of treatment date, day 97).
Interventions
- DRUG ticagrelor
- DRUG Acetylsalicylic acid (ASA)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 13,307 participants |
| Start Date | 2014-01-07 |
| Est. Completion | 2016-03-02 |
| Phase | Phase 3 |
What the finished NCT01994720 record still lists
NCT01994720 is an interventional study that assigns participants to a tested intervention. Its 13,307 participants enrollment target places it among the larger protocols in the corpus, above the 771-participant average among 15,282 other Phase 3 trials with a reported enrollment target (1626% higher).
The record links to 0 conditions, and to 2 interventions - of which ticagrelor is the first listed.
NCT01994720 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01994720 about?
NCT01994720 is a clinical study titled "[SOCRATES -Acute Stroke Or Transient IsChaemic Attack TReated With Aspirin or Ticagrelor and Patient OutcomES]". The primary objective of the study is to compare the effect of 90-day treatment with ticagrelor (180 mg \[two 90 mg tablets\] loading dose on Day 1 followed by 90 mg twice daily maintenance dose for the remainder of the study) vs acetylsalicylic acid (ASA)-aspirin (300 mg \[three 100 mg tablets\] lo...
What is the current status of trial NCT01994720?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 13,307 participants. The study started on 2014-01-07. Estimated completion is 2016-03-02.
What interventions are being tested in trial NCT01994720?
The interventions under investigation include: ticagrelor (DRUG), Acetylsalicylic acid (ASA) (DRUG).
Who is sponsoring clinical trial NCT01994720?
This trial is sponsored by AstraZeneca, which has 1,285 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01994720's enrollment target sits among peer trials
13,307 17th of 2000 higher than 1,984 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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