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NCT01984164 · ClinicalTrials.gov registry record · Phase 2
CAndesartan vs LIsinopril Effects on the BRain
A Phase 2 study, sponsored by Emory University.
- Completed
- Registry status
- Phase 2
- Development phase
- 176
- Enrollment target
NCT01984164: Completed Phase 2 study, sponsored by Emory University.
NCT01984164 is a Phase 2 study that has completed, run by Emory University. The registered enrollment target is 176 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (32% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01984164, a Phase 2 study, has completed, sponsored by Emory University.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 176 participants
- Enrollment target
Study Summary
The aim of this study is to conduct a 1-year double blind randomized control trial comparing candesartan to lisinopril in 140 individuals with hypertension and executive mild cognitive impairment in their effects on executive function, neuroimaging markers, and vascular indicators.
Primary Outcome
Executive function will be assessed using Trail Making Test (part B-A). Part A was collected to correct for motor speed and visual-perceptual demands on TMT by subtracting completion time for TMT Part A from completion time for Part B (TMT B - A). TMT Part B-A provides a relatively purer measure of executive functioning. It has a timed scale from 0 sec (min) to 300 secs (max). Along this scale, a lower score is better.
Interventions
- DRUG Lisinopril
- DRUG Candesartan
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 176 participants |
| Start Date | 2014-08-20 |
| Est. Completion | 2018-12-03 |
| Phase | Phase 2 |
What the finished NCT01984164 record still lists
NCT01984164 is an interventional study that assigns participants to a tested intervention. The registered 176 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (32% higher).
The record links to 0 conditions, and to 2 interventions - of which Lisinopril is the first listed.
NCT01984164 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01984164 about?
NCT01984164 is a clinical study titled "CAndesartan vs LIsinopril Effects on the BRain". The aim of this study is to conduct a 1-year double blind randomized control trial comparing candesartan to lisinopril in 140 individuals with hypertension and executive mild cognitive impairment in their effects on executive function, neuroimaging markers, and vascular indicators.
What is the current status of trial NCT01984164?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 176 participants. The study started on 2014-08-20. Estimated completion is 2018-12-03.
What interventions are being tested in trial NCT01984164?
The interventions under investigation include: Lisinopril (DRUG), Candesartan (DRUG).
Who is sponsoring clinical trial NCT01984164?
This trial is sponsored by Emory University, which has 1,208 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01984164's enrollment target sits among peer trials
176 394th of 2000 higher than 1,605 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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