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NCT01981772 · ClinicalTrials.gov registry record · NA

Efficacy of Buffered Lidocaine in Patients With Facial Swelling

A NA study, sponsored by Ohio State University.

Completed
Registry status
NA
Development phase
88
Enrollment target

NCT01981772: Completed NA study, sponsored by Ohio State University.

NCT01981772 is a NA study that has completed, run by Ohio State University. The registered enrollment target is 88 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (94% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01981772, a NA study, has completed, sponsored by Ohio State University.

COMPLETED
Registry status
NA
Development phase
88 participants
Enrollment target

Study Summary

The purpose of this study is to determine the clinical efficacy of a buffered 4% lidocaine solution for incision and drainage. Ninety patients will be examined clinically to determine a diagnosis of cellulitis or fluctuance. The diagnosis will be confirmed by incision and drainage. Patients will receive either 3.6 ml 4% lidocaine with 1:100,000 epinephrine or 3.6 ml 4% lidocaine with 1:100,000 epinephrine buffered with 8.4% sodium bicarbonate. Patients will rate pain prior to and throughout the procedure.

Primary Outcome

Patients will rate pain on a Heft-Parker visual analog scale during needle insertion, placement, and solution deposition phases of the anesthetic injection(s). Patients will also rate pain during the incision and dissection phases of the incision and drainage procedure. The number of millimeters along the scale are reported. No pain corresponded to 0 mm. Mild pain was defined as greater than 0 mm and less than or equal to 54 mm. Mild pain included the descriptors of "faint", "weak", and "mild pa

Interventions

  • DRUG 4% lidocaine with 1:100,000 epinephrine
  • DRUG 4% buffered lidocaine with 1:100,000 epinephrine

Trial Details

FieldValue
Enrollment Target 88 participants
Start Date 2013-03
Est. Completion 2014-06
Phase NA
Ohio State University

552 total trials

What the finished NCT01981772 record still lists

NCT01981772 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 88 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (94% lower).

The record links to 0 conditions, and to 2 interventions - of which 4% lidocaine with 1:100,000 epinephrine is the first listed.

NCT01981772 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01981772 about?

NCT01981772 is a clinical study titled "Efficacy of Buffered Lidocaine in Patients With Facial Swelling". The purpose of this study is to determine the clinical efficacy of a buffered 4% lidocaine solution for incision and drainage. Ninety patients will be examined clinically to determine a diagnosis of cellulitis or fluctuance. The diagnosis will be confirmed by incision and drainage. Patients will rec...

What is the current status of trial NCT01981772?

This trial is currently completed. It is a NA study. The enrollment target is 88 participants. The study started on 2013-03. Estimated completion is 2014-06.

What interventions are being tested in trial NCT01981772?

The interventions under investigation include: 4% lidocaine with 1:100,000 epinephrine (DRUG), 4% buffered lidocaine with 1:100,000 epinephrine (DRUG).

Who is sponsoring clinical trial NCT01981772?

This trial is sponsored by Ohio State University, which has 552 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01981772's enrollment target sits among peer trials

88 972nd of 2000 higher than 1,027 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01981772, the US trial registry maintained by the National Library of Medicine. NCT01981772 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.