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NCT01969669 · ClinicalTrials.gov registry record · Phase 1
A Study to Assess the Effect of Ketoconazole on the Metabolism of ABT-199
A Phase 1 study of Non-Hodgkin's Lymphoma, sponsored by AbbVie.
- Completed
- Registry status
- Phase 1
- Development phase
- 12
- Enrollment target
- 3
- Study locations
NCT01969669: Completed Phase 1 study of Non-Hodgkin's Lymphoma, sponsored by AbbVie.
NCT01969669 is a Phase 1 study of Non-Hodgkin's Lymphoma that has completed, run by AbbVie. The registered enrollment target is 12 participants, below the 222-participant average among 63 other Non-Hodgkin's Lymphoma trials with a reported enrollment target (95% lower). The trial reports 3 study locations across 3 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01969669, a Phase 1 study of Non-Hodgkin's Lymphoma, has completed, sponsored by AbbVie.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 12 participants
- Enrollment target
- 3
- Study locations
Study Summary
This is an open-label multicenter, study to assess the pharmacokinetic interaction of ketoconazole with ABT-199 in up to 12 subjects with relapsed or refractory non-Hodgkin's lymphoma.
Primary Outcome
Blood samples for pharmacokinetic (PK) analysis of ABT-199 will be collected at designated timepoints to assess the PK parameters for ABT-199 alone relative to ABT-199 with ketoconazole
Conditions Studied
Interventions
- DRUG Ketoconazole
- DRUG ABT-199
Study Locations (3)
Arizona
- Site Reference ID/Investigator# 97498 - Tucson
New Hampshire
- Site Reference ID/Investigator# 92593 - Lebanon
New Jersey
- Site Reference ID/Investigator# 101415 - Hackensack
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 12 participants |
| Start Date | 2013-12 |
| Est. Completion | 2014-09 |
| Phase | Phase 1 |
What the finished NCT01969669 record still lists
NCT01969669 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 12 participants, a relatively small participant target, below the 222-participant average among 63 other Non-Hodgkin's Lymphoma trials with a reported enrollment target (95% lower).
The record links to 1 condition, with Non-Hodgkin's Lymphoma appearing as the primary indexed condition, and to 2 interventions - of which Ketoconazole is the first listed.
NCT01969669 reports a single indexed study location in Arizona, New Hampshire, New Jersey.
Frequently Asked Questions
What is clinical trial NCT01969669 about?
NCT01969669 is a clinical study titled "A Study to Assess the Effect of Ketoconazole on the Metabolism of ABT-199". This is an open-label multicenter, study to assess the pharmacokinetic interaction of ketoconazole with ABT-199 in up to 12 subjects with relapsed or refractory non-Hodgkin's lymphoma.
What is the current status of trial NCT01969669?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 12 participants. The study started on 2013-12. Estimated completion is 2014-09.
What conditions does trial NCT01969669 study?
This clinical trial studies the following conditions: Non-Hodgkin's Lymphoma.
What interventions are being tested in trial NCT01969669?
The interventions under investigation include: Ketoconazole (DRUG), ABT-199 (DRUG).
Who is sponsoring clinical trial NCT01969669?
This trial is sponsored by AbbVie, which has 526 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01969669 being conducted?
This trial has 3 study locations across Arizona, New Hampshire, New Jersey. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Non-Hodgkin's Lymphoma
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Where NCT01969669's enrollment target sits among peer trials
12 55th of 63 higher than 7 of 63 other Non-Hodgkin's Lymphoma trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Non-Hodgkin's Lymphoma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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