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NCT01966666 · ClinicalTrials.gov registry record · Phase 1

A Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Preliminary Efficacy Study of TPI-287 in Alzheimer's Disease

A Phase 1 study, sponsored by University of California, San Francisco.

Completed
Registry status
Phase 1
Development phase
29
Enrollment target

NCT01966666 is a Phase 1 study that has completed, run by University of California, San Francisco. The registered enrollment target is 29 participants.

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The verdict

NCT01966666, a Phase 1 study, has completed, sponsored by University of California, San Francisco.

COMPLETED
Registry status
Phase 1
Development phase
29 participants
Enrollment target

Study Summary

The purpose of the study is to determine the highest dose of TPI-287 that is safe and tolerable when administered as an intravenous infusion to participants with mild to moderate Alzheimer's disease (AD), to measure pharmacokinetic properties of the drug as well as to gauge preliminary efficacy of TPI-287 on disease progression.

Interventions

  • DRUG Placebo
  • DRUG TPI-287 20 mg/m2
  • DRUG TPI-287 6.3 mg/m2
  • DRUG TPI-287 2 mg/m2

Trial Details

FieldValue
Enrollment Target 29 participants
Start Date 2013-11
Est. Completion 2019-09
Phase Phase 1

What the Registry Record Tells You About NCT01966666

The ClinicalTrials.gov registry entry for NCT01966666 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 29 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of California, San Francisco, which has 1,713 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 4 interventions - of which Placebo is the first listed.

NCT01966666 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01966666 about?

NCT01966666 is a clinical study titled "A Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Preliminary Efficacy Study of TPI-287 in Alzheimer's Disease". The purpose of the study is to determine the highest dose of TPI-287 that is safe and tolerable when administered as an intravenous infusion to participants with mild to moderate Alzheimer's disease (AD), to measure pharmacokinetic properties of the drug as well as to gauge preliminary efficacy of T...

What is the current status of trial NCT01966666?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 29 participants. The study started on 2013-11. Estimated completion is 2019-09.

What interventions are being tested in trial NCT01966666?

The interventions under investigation include: Placebo (DRUG), TPI-287 20 mg/m2 (DRUG), TPI-287 6.3 mg/m2 (DRUG), TPI-287 2 mg/m2 (DRUG).

Who is sponsoring clinical trial NCT01966666?

This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.