Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT01954017 · ClinicalTrials.gov registry record · Phase 1

STP206 for the Prevention of Necrotizing Enterocolitis (NEC)

A Phase 1 study, sponsored by Leadiant Biosciences.

Completed
Registry status
Phase 1
Development phase
103
Enrollment target

NCT01954017: Completed Phase 1 study, sponsored by Leadiant Biosciences.

NCT01954017 is a Phase 1 study that has completed, run by Leadiant Biosciences. The registered enrollment target is 103 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (72% higher). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT01954017, a Phase 1 study, has completed, sponsored by Leadiant Biosciences.

COMPLETED
Registry status
Phase 1
Development phase
103 participants
Enrollment target

Study Summary

This study is a sequential dose escalation study to assess the safety, tolerability, and preliminary NEC-preventative efficacy of two doses of STP206 versus control in very low birth weight and extremely low birth weight neonates.

Primary Outcome

The number and severity of adverse events, adverse events leading to study drug discontinuation, and number of deaths experienced by subjects randomized to the low-dose treatment groups

Interventions

  • OTHER Control
  • BIOLOGICAL STP206

Trial Details

FieldValue
Enrollment Target 103 participants
Start Date 2014-01-30
Est. Completion 2018-10-22
Phase Phase 1
Leadiant Biosciences

4 total trials

What the finished NCT01954017 record still lists

NCT01954017 is an interventional study that assigns participants to a tested intervention. The registered 103 participants enrollment target is mid-sized for trials with a published cap, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (72% higher).

The record links to 0 conditions, and to 2 interventions - of which Control is the first listed.

NCT01954017 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01954017 about?

NCT01954017 is a clinical study titled "STP206 for the Prevention of Necrotizing Enterocolitis (NEC)". This study is a sequential dose escalation study to assess the safety, tolerability, and preliminary NEC-preventative efficacy of two doses of STP206 versus control in very low birth weight and extremely low birth weight neonates.

What is the current status of trial NCT01954017?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 103 participants. The study started on 2014-01-30. Estimated completion is 2018-10-22.

What interventions are being tested in trial NCT01954017?

The interventions under investigation include: Control (OTHER), STP206 (BIOLOGICAL).

Who is sponsoring clinical trial NCT01954017?

This trial is sponsored by Leadiant Biosciences, which has 4 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01954017's enrollment target sits among peer trials

103 541st of 2000 higher than 1,458 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT04690348 · 103 participants · Phase 2

    Intracavitary Carrier-embedded Cs131 Brachytherapy for Recurrent Brain Metastases: a Randomized Phase II Study

  • NCT05282277 · 103 participants · Phase 4

    Examining the Effects of Estradiol on Neural and Molecular Response to Reward

  • NCT05566769 · 103 participants · NA

    Performance and Safety of a Digital Tool for Unsupervised Self-assessment of NMOSD

  • NCT05834478 · 103 participants · Phase 3

    Non-invasive Vagal Nerve Stimulation in Opioid Use Disorders UH3

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT01954017, the US trial registry maintained by the National Library of Medicine. NCT01954017 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.