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NCT01948947 · ClinicalTrials.gov registry record · NA

Improving Functions in MTBI Patients With Headache by rTMS

A NA study, sponsored by VA Office of Research and Development.

Completed
Registry status
NA
Development phase
29
Enrollment target

NCT01948947: Completed NA study, sponsored by VA Office of Research and Development.

NCT01948947 is a NA study that has completed, run by VA Office of Research and Development. The registered enrollment target is 29 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01948947, a NA study, has completed, sponsored by VA Office of Research and Development.

COMPLETED
Registry status
NA
Development phase
29 participants
Enrollment target

Study Summary

Due to recent wars in Afghanistan and Iraq, the number of Veteran suffering from Mild traumatic brain(MTBI) injury and PTSD increases rapidly. Headache is one of the most debilitating clinical symptoms in Veteran with MTBI and the cause of it is still not entirely clear. Recently, the use of non-invasive brain stimulation such as repetitive transcranial magnetic stimulation(rTMS) has yielded favorable clinical outcome in a few intractable chronic central pain conditions including headaches. This study aims to 1) assess the effect of rTMS in relieving headache and improving neurophysiological functions; and 2)explore the neuronal mechanisms associated with MTBI related headache and the analgesic effect of rTMS with function magnetic resonance imaging (fMRI).

Primary Outcome

The primary outcome time-point measurement will be averaged from each day the subject is enrolled in the study for each of the 3 time point periods: pre-treatment baseline, 1-week follow-up and 1-month follow-up. The results depict change in the composite score: intensity (scale of 0-10) x duration (# of hours) x frequency (# headaches per week). The larger composite score for each subject, the worse the debilitating headaches.

Interventions

  • DEVICE Transcranial Magnetic Stimulation
  • DEVICE Sham Transcranial Magnetic Stimulation

Trial Details

FieldValue
Enrollment Target 29 participants
Start Date 2014-05
Est. Completion 2016-09
Phase NA
VA Office of Research and Development

1,668 total trials

What the finished NCT01948947 record still lists

NCT01948947 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 29 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).

The record links to 0 conditions, and to 2 interventions - of which Transcranial Magnetic Stimulation is the first listed.

NCT01948947 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01948947 about?

NCT01948947 is a clinical study titled "Improving Functions in MTBI Patients With Headache by rTMS". Due to recent wars in Afghanistan and Iraq, the number of Veteran suffering from Mild traumatic brain(MTBI) injury and PTSD increases rapidly. Headache is one of the most debilitating clinical symptoms in Veteran with MTBI and the cause of it is still not entirely clear. Recently, the use of non-inv...

What is the current status of trial NCT01948947?

This trial is currently completed. It is a NA study. The enrollment target is 29 participants. The study started on 2014-05. Estimated completion is 2016-09.

What interventions are being tested in trial NCT01948947?

The interventions under investigation include: Transcranial Magnetic Stimulation (DEVICE), Sham Transcranial Magnetic Stimulation (DEVICE).

Who is sponsoring clinical trial NCT01948947?

This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01948947's enrollment target sits among peer trials

29 1702nd of 2000 higher than 297 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01948947, the US trial registry maintained by the National Library of Medicine. NCT01948947 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.