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NCT01928732 · ClinicalTrials.gov registry record · NA
Comparative Effectiveness Research in Veterans With PTSD
A NA study, sponsored by VA Office of Research and Development.
- Completed
- Registry status
- NA
- Development phase
- 916
- Enrollment target
NCT01928732: Completed NA study, sponsored by VA Office of Research and Development.
NCT01928732 is a NA study that has completed, run by VA Office of Research and Development. The registered enrollment target is 916 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01928732, a NA study, has completed, sponsored by VA Office of Research and Development.
- COMPLETED
- Registry status
- NA
- Development phase
- 916 participants
- Enrollment target
Study Summary
VA Cooperative Study CSP #591 is designed to compare the effectiveness of two types of psychotherapy, Prolonged Exposure (PE) and Cognitive Processing Therapy (CPT), for treating posttraumatic stress disorder (PTSD) in male and female Veterans. Despite solid evidence that both treatments are effective in Veterans and non-Veterans, there is a lack of evidence about the effectiveness of these treatments compared with one another. The sample will include 900 male and female Veterans with PTSD due to any traumatic military event. Veterans who are eligible and agree to participate in the study will be randomly assigned (by chance) to receive Prolonged Exposure or Cognitive Processing Therapy. The standard "dose" of treatment is 12 weekly sessions but Veterans who improve more rapidly may finish in fewer sessions and Veterans who improve more slowly may have additional sessions. The primary outcome is improvement in PTSD symptoms after treatment. The outcome will be measured at regular follow-up visits that will occur at the middle and at the end of treatment and then 3 and 6 months later. The investigators will measure other outcomes, including additional mental health problems, functioning, quality of life, and use of treatments for mental and physical problems. The investigators also will measure Veterans' treatment preference and examine whether Veterans who get the treatment they prefer do better than Veterans who get the less-preferred treatment. As a large multi-site trial with men and women, CSP #591 is designed to provide conclusive information about whether one treatment is better than the other, overall and for different types of patients-for example, men vs. women, combat Veterans vs. Veterans who experienced military sexual trauma, and older vs. younger Veterans. Regardless of the outcome, patients will have more information to help them make an informed decisions about which treatment to choose and VA will have stronger evidence to help make care Veteran-c
Interventions
- BEHAVIORAL Prolonged Exposure (PE)
- BEHAVIORAL Cognitive Processing Therapy (CPT)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 916 participants |
| Start Date | 2014-10-31 |
| Est. Completion | 2019-04-18 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01928732
The ClinicalTrials.gov registry entry for NCT01928732 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 916 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is VA Office of Research and Development, which has 1,668 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Prolonged Exposure (PE) is the first listed.
NCT01928732 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT01928732 about?
NCT01928732 is a clinical study titled "Comparative Effectiveness Research in Veterans With PTSD". VA Cooperative Study CSP #591 is designed to compare the effectiveness of two types of psychotherapy, Prolonged Exposure (PE) and Cognitive Processing Therapy (CPT), for treating posttraumatic stress disorder (PTSD) in male and female Veterans. Despite solid evidence that both treatments are effecti...
What is the current status of trial NCT01928732?
This trial is currently completed. It is a NA study. The enrollment target is 916 participants. The study started on 2014-10-31. Estimated completion is 2019-04-18.
What interventions are being tested in trial NCT01928732?
The interventions under investigation include: Prolonged Exposure (PE) (BEHAVIORAL), Cognitive Processing Therapy (CPT) (BEHAVIORAL).
Who is sponsoring clinical trial NCT01928732?
This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.
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