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NCT01910818 · ClinicalTrials.gov registry record · NA
Pilot Study of the Effect of Laser on Reversing Chronic Radiation Injury
A NA study of Chronic Radiation Dermatitis, sponsored by Massachusetts General Hospital.
- Active
- Registry status
- NA
- Development phase
- 12
- Enrollment target
- 1
- Study location
NCT01910818 is a NA study of Chronic Radiation Dermatitis that is active but no longer recruiting, run by Massachusetts General Hospital. The registered enrollment target is 12 participants. The trial reports 1 study location across 1 state.
The verdict
NCT01910818, a NA study of Chronic Radiation Dermatitis, is active but no longer recruiting, sponsored by Massachusetts General Hospital.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 12 participants
- Enrollment target
- 1
- Study location
Study Summary
Radiotherapy, an essential modality in cancer treatment, frequently induces a fibrotic process in the skin which can lead to increased risk of malignancy, poor wound healing, pain and limitation of movement, and permanent loss of skin appendages with hyper/hypopigmentation, decreased sweating and xerosis, posing significant cosmetic and quality of life issues. Advances in laser therapy has led to the use of fractional laser treatment (FLT) to treat fibrosis associated with in hypertrophic scars and morphea, leading to tissue repair, scar remodeling. The investigators propose a pilot clinical study to test the hypothesis that FLT can normalize the fibrotic process and induce normal scar remodeling in patients affected by chronic radiation injury. Understanding and correcting this underlying fibrotic process can help restore normal skin functions in patients affected with chronic radiation dermatitis (RD) and other debilitating fibrotic diseases in dermatology such as scleroderma, morphea, or nephrogenic systemic fibrosis.
Conditions Studied
Interventions
- OTHER No treatment
- DEVICE Fractional CO2 laser treatment
Study Locations (1)
Massachusetts
- Wellman Center for Photomedicine, Massachusetts General Hospital - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 12 participants |
| Start Date | 2013-11 |
| Est. Completion | 2026-08 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01910818
The ClinicalTrials.gov registry entry for NCT01910818 describes a study currently listed as active not recruiting, categorized as NA. The registered enrollment target is 12 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Massachusetts General Hospital, which has 2,032 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Chronic Radiation Dermatitis appearing as the primary indexed condition, and to 2 interventions - of which No treatment is the first listed.
NCT01910818 reports 1 study location spanning 1 distinct geographic area - top geographies include Massachusetts.
Frequently Asked Questions
What is clinical trial NCT01910818 about?
NCT01910818 is a clinical study titled "Pilot Study of the Effect of Laser on Reversing Chronic Radiation Injury". Radiotherapy, an essential modality in cancer treatment, frequently induces a fibrotic process in the skin which can lead to increased risk of malignancy, poor wound healing, pain and limitation of movement, and permanent loss of skin appendages with hyper/hypopigmentation, decreased sweating and xe...
What is the current status of trial NCT01910818?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 12 participants. The study started on 2013-11. Estimated completion is 2026-08.
What conditions does trial NCT01910818 study?
This clinical trial studies the following conditions: Chronic Radiation Dermatitis.
What interventions are being tested in trial NCT01910818?
The interventions under investigation include: No treatment (OTHER), Fractional CO2 laser treatment (DEVICE).
Who is sponsoring clinical trial NCT01910818?
This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01910818 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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