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NCT01910818 · ClinicalTrials.gov registry record · NA
Pilot Study of the Effect of Laser on Reversing Chronic Radiation Injury
A NA study of Chronic Radiation Dermatitis, sponsored by Massachusetts General Hospital.
- Active
- Registry status
- NA
- Development phase
- 12
- Enrollment target
- 1
- Study location
NCT01910818: Active NA study of Chronic Radiation Dermatitis, sponsored by Massachusetts General Hospital.
NCT01910818 is a NA study of Chronic Radiation Dermatitis that is active but no longer recruiting, run by Massachusetts General Hospital. The registered enrollment target is 12 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01910818, a NA study of Chronic Radiation Dermatitis, is active but no longer recruiting, sponsored by Massachusetts General Hospital.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 12 participants
- Enrollment target
- 1
- Study location
Study Summary
Radiotherapy, an essential modality in cancer treatment, frequently induces a fibrotic process in the skin which can lead to increased risk of malignancy, poor wound healing, pain and limitation of movement, and permanent loss of skin appendages with hyper/hypopigmentation, decreased sweating and xerosis, posing significant cosmetic and quality of life issues. Advances in laser therapy has led to the use of fractional laser treatment (FLT) to treat fibrosis associated with in hypertrophic scars and morphea, leading to tissue repair, scar remodeling. The investigators propose a pilot clinical study to test the hypothesis that FLT can normalize the fibrotic process and induce normal scar remodeling in patients affected by chronic radiation injury. Understanding and correcting this underlying fibrotic process can help restore normal skin functions in patients affected with chronic radiation dermatitis (RD) and other debilitating fibrotic diseases in dermatology such as scleroderma, morphea, or nephrogenic systemic fibrosis.
Conditions Studied
Interventions
- OTHER No treatment
- DEVICE Fractional CO2 laser treatment
Study Locations (1)
Massachusetts
- Wellman Center for Photomedicine, Massachusetts General Hospital - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 12 participants |
| Start Date | 2013-11 |
| Est. Completion | 2026-08 |
| Phase | NA |
What the registry record for NCT01910818 still lists
NCT01910818 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 12 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 1 condition, with Chronic Radiation Dermatitis appearing as the primary indexed condition, and to 2 interventions - of which No treatment is the first listed.
NCT01910818 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT01910818 about?
NCT01910818 is a clinical study titled "Pilot Study of the Effect of Laser on Reversing Chronic Radiation Injury". Radiotherapy, an essential modality in cancer treatment, frequently induces a fibrotic process in the skin which can lead to increased risk of malignancy, poor wound healing, pain and limitation of movement, and permanent loss of skin appendages with hyper/hypopigmentation, decreased sweating and xe...
What is the current status of trial NCT01910818?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 12 participants. The study started on 2013-11. Estimated completion is 2026-08.
What conditions does trial NCT01910818 study?
This clinical trial studies the following conditions: Chronic Radiation Dermatitis.
What interventions are being tested in trial NCT01910818?
The interventions under investigation include: No treatment (OTHER), Fractional CO2 laser treatment (DEVICE).
Who is sponsoring clinical trial NCT01910818?
This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01910818 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01910818's enrollment target sits among peer trials
12 1913th of 2000 higher than 74 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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