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NCT01897441 · ClinicalTrials.gov registry record · NA

Chemotherapy Before Surgery and Tissue Sample Collection in Patients With Stage IIA-IIIC Breast Cancer

A NA study, sponsored by Albert Einstein College of Medicine.

Terminated
Registry status
NA
Development phase
31
Enrollment target

NCT01897441: Clinical Trial NA study, sponsored by Albert Einstein College of Medicine.

NCT01897441 is a NA study that was terminated before completion, run by Albert Einstein College of Medicine. The registered enrollment target is 31 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01897441, a NA study, was terminated before completion, sponsored by Albert Einstein College of Medicine.

TERMINATED
Registry status
NA
Development phase
31 participants
Enrollment target

Study Summary

This pilot clinical trial studies chemotherapy before surgery and tissue sample collection in patients with stage IIA-IIIC breast cancer. Drugs used in chemotherapy, such as doxorubicin hydrochloride, cyclophosphamide, and paclitaxel, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Monoclonal antibodies, such as trastuzumab, may interfere with the ability of tumor cells to grow and spread. Giving doxorubicin hydrochloride, cyclophosphamide, paclitaxel and trastuzumab may kill more tumor cells. Collecting and storing samples of tissue from patients with breast cancer to study in the laboratory may help doctors learn more about how well patients will respond to treatment.

Primary Outcome

Descriptive statistics by treatment group will be presented. The two-sampled t-test will be performed. Appropriate transformation may be used to improve normality of the outcome variable.

Interventions

  • DRUG Cyclophosphamide
  • OTHER Laboratory Biomarker Analysis
  • DRUG Paclitaxel
  • DRUG Doxorubicin Hydrochloride
  • OTHER Cytology Specimen Collection Procedure

Trial Details

FieldValue
Enrollment Target 31 participants
Start Date 2013-06
Est. Completion 2023-10-25
Phase NA
Albert Einstein College of Medicine

175 total trials

Why NCT01897441 stopped before completion

NCT01897441 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 31 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).

The record links to 0 conditions, and to 5 interventions - of which Cyclophosphamide is the first listed.

NCT01897441 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01897441 about?

NCT01897441 is a clinical study titled "Chemotherapy Before Surgery and Tissue Sample Collection in Patients With Stage IIA-IIIC Breast Cancer". This pilot clinical trial studies chemotherapy before surgery and tissue sample collection in patients with stage IIA-IIIC breast cancer. Drugs used in chemotherapy, such as doxorubicin hydrochloride, cyclophosphamide, and paclitaxel, work in different ways to stop the growth of tumor cells, either ...

What is the current status of trial NCT01897441?

This trial is currently terminated. It is a NA study. The enrollment target is 31 participants. The study started on 2013-06. Estimated completion is 2023-10-25.

What interventions are being tested in trial NCT01897441?

The interventions under investigation include: Cyclophosphamide (DRUG), Laboratory Biomarker Analysis (OTHER), Paclitaxel (DRUG), Doxorubicin Hydrochloride (DRUG), Cytology Specimen Collection Procedure (OTHER).

Who is sponsoring clinical trial NCT01897441?

This trial is sponsored by Albert Einstein College of Medicine, which has 175 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01897441's enrollment target sits among peer trials

31 1592nd of 2000 higher than 408 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01897441, the US trial registry maintained by the National Library of Medicine. NCT01897441 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.