Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT01886586 · ClinicalTrials.gov registry record · NA
Retaining Cognition While Avoiding Late-Life Depression
A NA study of Mild Cognitive Impairment, sponsored by University of Pittsburgh.
- Completed
- Registry status
- NA
- Development phase
- 94
- Enrollment target
- 2
- Study locations
NCT01886586: Completed NA study of Mild Cognitive Impairment, sponsored by University of Pittsburgh.
NCT01886586 is a NA study of Mild Cognitive Impairment that has completed, run by University of Pittsburgh. The registered enrollment target is 94 participants, below the 1,270-participant average among 205 other Mild Cognitive Impairment trials with a reported enrollment target (93% lower). The trial reports 2 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01886586, a NA study of Mild Cognitive Impairment, has completed, sponsored by University of Pittsburgh.
- COMPLETED
- Registry status
- NA
- Development phase
- 94 participants
- Enrollment target
- 2
- Study locations
Study Summary
This study will adapt Problem Solving Therapy (PST) for individuals with mild cognitive impairment (MCI) as an intervention for preventing major depression (DEP). PST will be modified so as to be provided to both MCI probands as well as their support person. The primary aim is to examine the effectiveness of PST in individuals with MCI and the support person, at preventing DEP over 12 mos. in MCI probands. We also will examine the effect of exercise on preventing depression.
Primary Outcome
PHQ9, prime-MD SCID, GAD7
Conditions Studied
Interventions
- OTHER Enhanced Usual Care
- BEHAVIORAL Problem Solving Therapy
- BEHAVIORAL Problem Solving Therapy + Exercise
Study Locations (2)
Pennsylvania
- UPMC Late-Life Evaluation and Treatment Center - Pittsburgh
- UPMC Western Psychiatric Institute and Clinic - Pittsburgh
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 94 participants |
| Start Date | 2011-07 |
| Est. Completion | 2016-07 |
| Phase | NA |
What the finished NCT01886586 record still lists
NCT01886586 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 94 participants, a relatively small participant target, below the 1,270-participant average among 205 other Mild Cognitive Impairment trials with a reported enrollment target (93% lower).
The record links to 1 condition, with Mild Cognitive Impairment appearing as the primary indexed condition, and to 3 interventions - of which Enhanced Usual Care is the first listed.
NCT01886586 reports a single indexed study location in Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT01886586 about?
NCT01886586 is a clinical study titled "Retaining Cognition While Avoiding Late-Life Depression". This study will adapt Problem Solving Therapy (PST) for individuals with mild cognitive impairment (MCI) as an intervention for preventing major depression (DEP). PST will be modified so as to be provided to both MCI probands as well as their support person. The primary aim is to examine the effecti...
What is the current status of trial NCT01886586?
This trial is currently completed. It is a NA study. The enrollment target is 94 participants. The study started on 2011-07. Estimated completion is 2016-07.
What conditions does trial NCT01886586 study?
This clinical trial studies the following conditions: Mild Cognitive Impairment.
What interventions are being tested in trial NCT01886586?
The interventions under investigation include: Enhanced Usual Care (OTHER), Problem Solving Therapy (BEHAVIORAL), Problem Solving Therapy + Exercise (BEHAVIORAL).
Who is sponsoring clinical trial NCT01886586?
This trial is sponsored by University of Pittsburgh, which has 1,238 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01886586 being conducted?
This trial has 2 study locations across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Mild Cognitive Impairment
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT01886586's enrollment target sits among peer trials
94 95th of 205 higher than 111 of 205 other Mild Cognitive Impairment trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Mild Cognitive Impairment trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Wayfinding Intervention and Long-Term Memory
RECRUITING · NA
-
Dual Task Perturbation Training for OAwMCI
RECRUITING · NA
-
Impact of Intensive Computerized Cognitive Training
RECRUITING · NA
-
Multimodal Investigation of Neural Plasticity
RECRUITING · NA
-
GAMES Intervention in MCI (Mild Cognitive Impairment)
RECRUITING · NA
-
A Feasiblity Study of Green Activity Program for People Living With Memory Challenges
RECRUITING · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT03747146 · 94 participants · NA
Enhanced Recovery After Surgery (ERAS) Total Knee Replacement (TKR) With a Transitional Pain Service
- NCT04061421 · 94 participants · Phase 1
Active Myeloid Target Compound Combinations in MDS/MPN Overlap Syndromes Overlap Syndromes (ABNL-MARRO)
- NCT04205968 · 94 participants · Phase 2
Ramucirumab and Paclitaxel or FOLFIRI in Advanced Small Bowel Cancers
- NCT04464759 · 94 participants · Phase 1
A Study of Nivolumab and Hydroxychloroquine or Nivolumab/Ipilimumab and Hydroxychloroquine in Advanced Melanoma
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia