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NCT01873768 · ClinicalTrials.gov registry record · Phase 4
Clinical Efficacy of Tranexamic Acid and ε-Aminocaproic Acid in Reducing Blood Loss Following Total Knee Replacement
A Phase 4 study of Osteoarthritis, sponsored by Miller Orthopedic Specialists.
- Completed
- Registry status
- Phase 4
- Development phase
- 194
- Enrollment target
- 1
- Study location
NCT01873768 is a Phase 4 study of Osteoarthritis that has completed, run by Miller Orthopedic Specialists. The registered enrollment target is 194 participants, below the 816-participant average among 135 other Osteoarthritis trials with a reported enrollment target (76% lower). The trial reports 1 study location across 1 state.
The verdict
NCT01873768, a Phase 4 study of Osteoarthritis, has completed, sponsored by Miller Orthopedic Specialists.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 194 participants
- Enrollment target
- 1
- Study location
Study Summary
Tranexamic acid (TXA) and ε-aminocaproic acid (EACA) are two drugs shown to limit blood loss following major surgery, from cardiac to orthopedic procedures. Yet compared to tranexamic acid (TXA), research on the clinical impact of ε-aminocaproic acid (EACA) in total knee arthroplasty (TKA) is limited. The primary aim of this study is to determine whether TXA and EACA provide similar blood decreasing effects following TKA or whether one drug provides a superior effect over the other in reducing patients' blood loss.
Conditions Studied
Interventions
- DRUG Tranexamic Acid (TXA)
- DRUG ε-Aminocaproic Acid (EACA)
Study Locations (1)
Iowa
- Miller Orthopedic Specialists - Council Bluffs
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 194 participants |
| Start Date | 2014-01 |
| Est. Completion | 2015-12 |
| Phase | Phase 4 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01873768
The ClinicalTrials.gov registry entry for NCT01873768 describes a study currently listed as completed, categorized as Phase 4. The registered enrollment target is 194 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 816-participant average among 135 other Osteoarthritis trials with a reported enrollment target (76% lower). The listed sponsor is Miller Orthopedic Specialists, which has 1 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Osteoarthritis appearing as the primary indexed condition, and to 2 interventions - of which Tranexamic Acid (TXA) is the first listed.
NCT01873768 reports 1 study location spanning 1 distinct geographic area - top geographies include Iowa.
Frequently Asked Questions
What is clinical trial NCT01873768 about?
NCT01873768 is a clinical study titled "Clinical Efficacy of Tranexamic Acid and ε-Aminocaproic Acid in Reducing Blood Loss Following Total Knee Replacement". Tranexamic acid (TXA) and ε-aminocaproic acid (EACA) are two drugs shown to limit blood loss following major surgery, from cardiac to orthopedic procedures. Yet compared to tranexamic acid (TXA), research on the clinical impact of ε-aminocaproic acid (EACA) in total knee arthroplasty (TKA) is limite...
What is the current status of trial NCT01873768?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 194 participants. The study started on 2014-01. Estimated completion is 2015-12.
What conditions does trial NCT01873768 study?
This clinical trial studies the following conditions: Osteoarthritis.
What interventions are being tested in trial NCT01873768?
The interventions under investigation include: Tranexamic Acid (TXA) (DRUG), ε-Aminocaproic Acid (EACA) (DRUG).
Who is sponsoring clinical trial NCT01873768?
This trial is sponsored by Miller Orthopedic Specialists, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01873768 being conducted?
This trial has 1 study location across Iowa. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
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