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NCT01862614 · ClinicalTrials.gov registry record · Phase 4
Testing the Anesthetic Effectiveness of Buffered Articaine Injected Next to a Lower First Molar.
A Phase 4 study, sponsored by Ohio State University.
- Completed
- Registry status
- Phase 4
- Development phase
- 80
- Enrollment target
NCT01862614 is a Phase 4 study that has completed, run by Ohio State University. The registered enrollment target is 80 participants.
The verdict
NCT01862614, a Phase 4 study, has completed, sponsored by Ohio State University.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 80 participants
- Enrollment target
Study Summary
Infiltration (injecting next to the tooth) injections are common in dentistry and a number of studies have shown that articaine anesthetic, when injected next to a lower molar, is more effective than a local anesthetic injection of lidocaine. However success rates have not been as high as hoped for. No objective study has addressed the success rate of buffering articaine in a mandibular primary buccal infiltration of the first molar. Therefore, the purpose of this prospective, randomized, double-blind, crossover study is to compare the degree of pulpal anesthesia obtained with a buffered 4% articaine with 1:100,000 epinephrine solution versus a non-buffered 4% articaine with 1:100,000 epinephrine solution as a primary infiltration in the mandibular first molar. The investigators will also record the pain of injection and postoperative pain.
Interventions
- DRUG Articaine Hydrochloride + Epinephrine
- DRUG Buffered Articaine Hydrochloride + Epinephrine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 80 participants |
| Start Date | 2013-04 |
| Est. Completion | 2014-05 |
| Phase | Phase 4 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01862614
The ClinicalTrials.gov registry entry for NCT01862614 describes a study currently listed as completed, categorized as Phase 4. The registered enrollment target is 80 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Ohio State University, which has 552 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Articaine Hydrochloride + Epinephrine is the first listed.
NCT01862614 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT01862614 about?
NCT01862614 is a clinical study titled "Testing the Anesthetic Effectiveness of Buffered Articaine Injected Next to a Lower First Molar.". Infiltration (injecting next to the tooth) injections are common in dentistry and a number of studies have shown that articaine anesthetic, when injected next to a lower molar, is more effective than a local anesthetic injection of lidocaine. However success rates have not been as high as hoped for....
What is the current status of trial NCT01862614?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 80 participants. The study started on 2013-04. Estimated completion is 2014-05.
What interventions are being tested in trial NCT01862614?
The interventions under investigation include: Articaine Hydrochloride + Epinephrine (DRUG), Buffered Articaine Hydrochloride + Epinephrine (DRUG).
Who is sponsoring clinical trial NCT01862614?
This trial is sponsored by Ohio State University, which has 552 total clinical trials registered on ClinicalTrials.gov.
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