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NCT01843517 · ClinicalTrials.gov registry record
Endogenous Pain Facilitation and Inhibition in Postpartum Women
A clinical trial, sponsored by Wake Forest University.
- Completed
- Registry status
- 80
- Enrollment target
NCT01843517: Completed study, sponsored by Wake Forest University.
NCT01843517 is a clinical trial that has completed, run by Wake Forest University. The registered enrollment target is 80 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01843517 has completed, sponsored by Wake Forest University.
- COMPLETED
- Registry status
- 80 participants
- Enrollment target
Study Summary
This study seeks to further understand these three observations - (1) that the time period surrounding childbirth accelerates recovery from pain after injury (2) that this likely reflects dampened facilitating mechanisms and exaggerated inhibitory mechanisms, and (3) that stress may interfere with this protection. In this study the investigators will compare women within 2 weeks of delivery to age matched controls and anticipate that pain inhibition is increased after delivery, pain facilitation is decreased, and that there is a relationship between these pain responses and the degree of pre-existing stress.
Primary Outcome
Hyperalgesia and allodynia on the skin of the forearm will be established by heating the forearm with a 4 cm2 Peltier controlled thermode (TSA®) to 45 degrees Celsius for 5 minutes. The investigators will then apply topical capsaicin (0.075% cream, Bioglan Pharmaceuticals) under an occlusive dressing at the same site as the thermal probe for 30 minutes. 40 minutes after removal of the capsaicin cream the site will be heated to 40 degrees Celsius for 5 minutes (rekindling) following the end of ca
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 80 participants |
| Start Date | 2013-04 |
| Est. Completion | 2017-12-05 |
What the finished NCT01843517 record still lists
NCT01843517 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 80 participants, a relatively small participant target.
The record links to 0 conditions, and to 0 interventions.
NCT01843517 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01843517 about?
NCT01843517 is a clinical study titled "Endogenous Pain Facilitation and Inhibition in Postpartum Women". This study seeks to further understand these three observations - (1) that the time period surrounding childbirth accelerates recovery from pain after injury (2) that this likely reflects dampened facilitating mechanisms and exaggerated inhibitory mechanisms, and (3) that stress may interfere with t...
What is the current status of trial NCT01843517?
This trial is currently completed. The enrollment target is 80 participants. The study started on 2013-04. Estimated completion is 2017-12-05.
Who is sponsoring clinical trial NCT01843517?
This trial is sponsored by Wake Forest University, which has 100 total clinical trials registered on ClinicalTrials.gov.
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