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NCT01826448 · ClinicalTrials.gov registry record · Phase 1

A Phase 1b Open Label, Dose Escalation Study of PLX3397 in Combination With Vemurafenib in V600-mutated BRAF Melanoma

A Phase 1 study, sponsored by Daiichi Sankyo.

Terminated
Registry status
Phase 1
Development phase
13
Enrollment target

NCT01826448 is a Phase 1 study that was terminated before completion, run by Daiichi Sankyo. The registered enrollment target is 13 participants.

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The verdict

NCT01826448, a Phase 1 study, was terminated before completion, sponsored by Daiichi Sankyo.

TERMINATED
Registry status
Phase 1
Development phase
13 participants
Enrollment target

Study Summary

The purpose of this research study is to test the safety of an investigational new drug called PLX3397 when used in combination with Vemurafenib (Zelboraf™) at different dose levels. Vemurafenib has been approved by the United States Food and Drug Administration (FDA)/European Medicines Agency (EMA) for the treatment of a specific category of unresectable or metastatic melanoma.

Interventions

  • DRUG vemurafenib
  • DRUG PLX3397

Trial Details

FieldValue
Enrollment Target 13 participants
Start Date 2013-11-05
Est. Completion 2014-09-22
Phase Phase 1

Sponsor

Daiichi Sankyo

236 total trials

What the Registry Record Tells You About NCT01826448

The ClinicalTrials.gov registry entry for NCT01826448 describes a study currently listed as terminated, categorized as Phase 1. The registered enrollment target is 13 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Daiichi Sankyo, which has 236 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which vemurafenib is the first listed.

NCT01826448 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01826448 about?

NCT01826448 is a clinical study titled "A Phase 1b Open Label, Dose Escalation Study of PLX3397 in Combination With Vemurafenib in V600-mutated BRAF Melanoma". The purpose of this research study is to test the safety of an investigational new drug called PLX3397 when used in combination with Vemurafenib (Zelboraf™) at different dose levels. Vemurafenib has been approved by the United States Food and Drug Administration (FDA)/European Medicines Agency (EMA)...

What is the current status of trial NCT01826448?

This trial is currently terminated. It is a Phase 1 study. The enrollment target is 13 participants. The study started on 2013-11-05. Estimated completion is 2014-09-22.

What interventions are being tested in trial NCT01826448?

The interventions under investigation include: vemurafenib (DRUG), PLX3397 (DRUG).

Who is sponsoring clinical trial NCT01826448?

This trial is sponsored by Daiichi Sankyo, which has 236 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.