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NCT01824173 · ClinicalTrials.gov registry record · Phase 1
Muscle Protein Metabolism in Obesity
A Phase 1 study, sponsored by Mayo Clinic.
- Completed
- Registry status
- Phase 1
- Development phase
- 84
- Enrollment target
NCT01824173: Completed Phase 1 study, sponsored by Mayo Clinic.
NCT01824173 is a Phase 1 study that has completed, run by Mayo Clinic. The registered enrollment target is 84 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (40% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01824173, a Phase 1 study, has completed, sponsored by Mayo Clinic.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 84 participants
- Enrollment target
Study Summary
Obesity is associated with reduced adenosine triphosphate (ATP) turnover in skeletal muscle, a condition that can impair muscle metabolism. The proposed research will discover mechanisms responsible for decreased content in mitochondrial proteins as well as in protein β-F1-ATPase, which is directly responsible for ATP assembly, in the muscle of obese individuals. This research will further examine the effectiveness of interventions, such as increased plasma amino acid availability and exercise, to increase the rate of production of mitochondrial proteins as well as that of β-F1-ATPase in the muscle of obese individuals. The findings will help to develop appropriate interventions to improve muscle ATP turnover and metabolism in obese people.
Interventions
- OTHER Aerobic exercise
- OTHER Increase in the levels of plasma amino acids
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 84 participants |
| Start Date | 2012-10 |
| Est. Completion | 2020-02-07 |
| Phase | Phase 1 |
What the finished NCT01824173 record still lists
NCT01824173 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 84 participants, a relatively small participant target, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (40% higher).
The record links to 0 conditions, and to 2 interventions - of which Aerobic exercise is the first listed.
NCT01824173 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01824173 about?
NCT01824173 is a clinical study titled "Muscle Protein Metabolism in Obesity". Obesity is associated with reduced adenosine triphosphate (ATP) turnover in skeletal muscle, a condition that can impair muscle metabolism. The proposed research will discover mechanisms responsible for decreased content in mitochondrial proteins as well as in protein β-F1-ATPase, which is directly ...
What is the current status of trial NCT01824173?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 84 participants. The study started on 2012-10. Estimated completion is 2020-02-07.
What interventions are being tested in trial NCT01824173?
The interventions under investigation include: Aerobic exercise (OTHER), Increase in the levels of plasma amino acids (OTHER).
Who is sponsoring clinical trial NCT01824173?
This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01824173's enrollment target sits among peer trials
84 659th of 2000 higher than 1,336 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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