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NCT01818414 · ClinicalTrials.gov registry record · NA
Same-day Dilapan-S With Adjunctive Misoprostol
A NA study, sponsored by University of Pittsburgh.
- Terminated
- Registry status
- NA
- Development phase
- 29
- Enrollment target
NCT01818414: Clinical Trial NA study, sponsored by University of Pittsburgh.
NCT01818414 is a NA study that was terminated before completion, run by University of Pittsburgh. The registered enrollment target is 29 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01818414, a NA study, was terminated before completion, sponsored by University of Pittsburgh.
- TERMINATED
- Registry status
- NA
- Development phase
- 29 participants
- Enrollment target
Study Summary
Cervical preparation before second trimester dilation and evacuation (D\&E) reduces risks and complications. Osmotic cervical dilators as well as prostaglandin analogues have been studied for cervical preparation. However, the optimal method for cervical preparation, especially for D\&E procedures that occur on the same day as cervical preparation, is not known. This study will investigate misoprostol versus placebo as an adjunct to Dilapan-S for cervical preparation for same-day D\&E between 16+0 and 20+6 weeks gestation. HYPOTHESIS: Administration of 400 µg buccal misoprostol compared to placebo at least 3 hours prior to D\&E as an adjunct to cervical preparation with Dilapan-S will decrease operative time for same-day D\&E performed between 16+0 and 20+6 weeks.
Primary Outcome
The primary outcome will be operative time. Operative time will be measured from initial passage of an instrument into the uterus to start the D\&E. The end of operative time will be measured by the removal of the last instrument from the uterus to complete the D\&E.
Interventions
- DRUG Misoprostol
- DRUG Folic Acid
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 29 participants |
| Start Date | 2013-10 |
| Est. Completion | 2014-04 |
| Phase | NA |
Why NCT01818414 stopped before completion
NCT01818414 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 29 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).
The record links to 0 conditions, and to 2 interventions - of which Misoprostol is the first listed.
NCT01818414 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01818414 about?
NCT01818414 is a clinical study titled "Same-day Dilapan-S With Adjunctive Misoprostol". Cervical preparation before second trimester dilation and evacuation (D\&E) reduces risks and complications. Osmotic cervical dilators as well as prostaglandin analogues have been studied for cervical preparation. However, the optimal method for cervical preparation, especially for D\&E procedures t...
What is the current status of trial NCT01818414?
This trial is currently terminated. It is a NA study. The enrollment target is 29 participants. The study started on 2013-10. Estimated completion is 2014-04.
What interventions are being tested in trial NCT01818414?
The interventions under investigation include: Misoprostol (DRUG), Folic Acid (DRUG).
Who is sponsoring clinical trial NCT01818414?
This trial is sponsored by University of Pittsburgh, which has 1,238 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01818414's enrollment target sits among peer trials
29 1702nd of 2000 higher than 297 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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