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NCT01783743 · ClinicalTrials.gov registry record · NA
Identification of TT Cases by Community Treatment Assistants: An Assessment
A NA study of Trichiasis, sponsored by Johns Hopkins University.
- Completed
- Registry status
- NA
- Development phase
- 27,473
- Enrollment target
- 1
- Study location
NCT01783743 is a NA study of Trichiasis that has completed, run by Johns Hopkins University. The registered enrollment target is 27,473 participants. The trial reports 1 study location across 1 state.
The verdict
NCT01783743, a NA study of Trichiasis, has completed, sponsored by Johns Hopkins University.
- COMPLETED
- Registry status
- NA
- Development phase
- 27,473 participants
- Enrollment target
- 1
- Study location
Study Summary
To achieve the goal of trachoma control as mandated by the World Health Organization, countries must reduce the backlog of trichiasis surgery cases to less than 1/1,000 of their population. However, these cases reside in rural villages in trachoma endemic districts, and finding them to offer services is a challenge. Community Treatment Assistants (CTAs) are village residents who are trained to offer Mass Drug Administration (MDA) to their communities and hence are in contact with most residents. A training guide and tool for screening for trachomatous trichiasis (TT) will be developed to train CTAs in rural Tanzania to identify cases in their communities and refer them to surgery. Compared to the current process by which CTAs passively screen for TT if cases complaint, investigators hypothesize that the trained CTAs will identify twice the usual number of TT surgery cases during ongoing community antibiotic administrations for trachoma and will also miss fewer cases. If this simple system is effective, it can be implemented widely to screen communities for cases of TT. Residents from thirty-six villages holding MDA, for whom a complete census is available, will be randomized on a 1:1 basis to intervention (where the CTAs receive the enhanced training from the enhanced training team) and usual assessment (where the CTAs receive the usual instructions from the regular MDA team). In both arms, the CTAs will keep records of all cases they have screened as positive for TT amongst the residents. A Master TT grader will grade all screened cases of TT to determine the rate of true positivity in both arms.In addition, he will examine a random sample of residents who are screened as negative to detect potentially missed cases and estimate the total burden of trichiasis cases in both arms as well.The assessments of the Master TT grader will serve as the gold standard for calculations of sensitivity, specificity, and positive and negative predictive values of the enhanced tra
Conditions Studied
Interventions
- OTHER TT Training Program and TT Screening Card
Study Locations (1)
Maryland
- Johns Hopkins University - Baltimore
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 27,473 participants |
| Start Date | 2013-02 |
| Est. Completion | 2013-12 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01783743
The ClinicalTrials.gov registry entry for NCT01783743 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 27,473 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Johns Hopkins University, which has 1,448 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Trichiasis appearing as the primary indexed condition, and to 1 intervention - of which TT Training Program and TT Screening Card is the first listed.
NCT01783743 reports 1 study location spanning 1 distinct geographic area - top geographies include Maryland.
Frequently Asked Questions
What is clinical trial NCT01783743 about?
NCT01783743 is a clinical study titled "Identification of TT Cases by Community Treatment Assistants: An Assessment". To achieve the goal of trachoma control as mandated by the World Health Organization, countries must reduce the backlog of trichiasis surgery cases to less than 1/1,000 of their population. However, these cases reside in rural villages in trachoma endemic districts, and finding them to offer service...
What is the current status of trial NCT01783743?
This trial is currently completed. It is a NA study. The enrollment target is 27,473 participants. The study started on 2013-02. Estimated completion is 2013-12.
What conditions does trial NCT01783743 study?
This clinical trial studies the following conditions: Trichiasis.
What interventions are being tested in trial NCT01783743?
The interventions under investigation include: TT Training Program and TT Screening Card (OTHER).
Who is sponsoring clinical trial NCT01783743?
This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01783743 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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