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NCT01763905 · ClinicalTrials.gov registry record · Phase 3
Goal Achievement After Utilizing an Anti-PCSK9 Antibody in Statin Intolerant Subjects -2
A Phase 3 study, sponsored by Amgen.
- Completed
- Registry status
- Phase 3
- Development phase
- 307
- Enrollment target
NCT01763905: Completed Phase 3 study, sponsored by Amgen.
NCT01763905 is a Phase 3 study that has completed, run by Amgen. The registered enrollment target is 307 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (60% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01763905, a Phase 3 study, has completed, sponsored by Amgen.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 307 participants
- Enrollment target
Study Summary
The primary objective was to evaluate the effect of 12 weeks of subcutaneous (SC) evolocumab every 2 weeks (Q2W) and monthly (QM), compared with ezetimibe, on percent change from baseline in low-density lipoprotein cholesterol (LDL-C) in hypercholesterolemic adults unable to tolerate an effective dose of a statin (HMG-CoA (5-hydroxy-3-methylglutaryl-coenzyme A) reductase inhibitors).
Interventions
- DRUG Ezetimibe
- BIOLOGICAL Evolocumab
- DRUG Placebo to Evolocumab
- DRUG Placebo to Ezetimibe
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 307 participants |
| Start Date | 2013-01-24 |
| Est. Completion | 2013-11-19 |
| Phase | Phase 3 |
What the finished NCT01763905 record still lists
NCT01763905 is an interventional study that assigns participants to a tested intervention. The registered 307 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (60% lower).
The record links to 0 conditions, and to 4 interventions - of which Ezetimibe is the first listed.
NCT01763905 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01763905 about?
NCT01763905 is a clinical study titled "Goal Achievement After Utilizing an Anti-PCSK9 Antibody in Statin Intolerant Subjects -2". The primary objective was to evaluate the effect of 12 weeks of subcutaneous (SC) evolocumab every 2 weeks (Q2W) and monthly (QM), compared with ezetimibe, on percent change from baseline in low-density lipoprotein cholesterol (LDL-C) in hypercholesterolemic adults unable to tolerate an effective do...
What is the current status of trial NCT01763905?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 307 participants. The study started on 2013-01-24. Estimated completion is 2013-11-19.
What interventions are being tested in trial NCT01763905?
The interventions under investigation include: Ezetimibe (DRUG), Evolocumab (BIOLOGICAL), Placebo to Evolocumab (DRUG), Placebo to Ezetimibe (DRUG).
Who is sponsoring clinical trial NCT01763905?
This trial is sponsored by Amgen, which has 558 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01763905's enrollment target sits among peer trials
307 1115th of 2000 higher than 886 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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