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NCT01758731 · ClinicalTrials.gov registry record · Phase 1

Study of Olaparib With Radiation Therapy and Cetuximab in Advanced Head and Neck Cancer With Heavy Smoking History

A Phase 1 study, sponsored by University of Colorado, Denver.

Completed
Registry status
Phase 1
Development phase
17
Enrollment target

NCT01758731 is a Phase 1 study that has completed, run by University of Colorado, Denver. The registered enrollment target is 17 participants.

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The verdict

NCT01758731, a Phase 1 study, has completed, sponsored by University of Colorado, Denver.

COMPLETED
Registry status
Phase 1
Development phase
17 participants
Enrollment target

Study Summary

This is a research study that plans to learn more about the safety and tolerability of an investigational drug called Olaparib, in combination with radiation therapy and cetuximab. Hypothesis: Intensity modulated radiotherapy with concurrent C225 and Olaparib represents a feasible, biologically-based alternative to standard chemoradiation, with acceptable toxicity, for treatment of locally-advanced HNSCC in patients having a ≥ 10 pack-year smoking history.

Interventions

  • DRUG Olaparib
  • RADIATION Radiation Therapy
  • DRUG Cetuximab

Trial Details

FieldValue
Enrollment Target 17 participants
Start Date 2012-10-22
Est. Completion 2018-10-31
Phase Phase 1

Sponsor

University of Colorado, Denver

1,283 total trials

What the Registry Record Tells You About NCT01758731

The ClinicalTrials.gov registry entry for NCT01758731 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 17 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Colorado, Denver, which has 1,283 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 3 interventions - of which Olaparib is the first listed.

NCT01758731 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01758731 about?

NCT01758731 is a clinical study titled "Study of Olaparib With Radiation Therapy and Cetuximab in Advanced Head and Neck Cancer With Heavy Smoking History". This is a research study that plans to learn more about the safety and tolerability of an investigational drug called Olaparib, in combination with radiation therapy and cetuximab. Hypothesis: Intensity modulated radiotherapy with concurrent C225 and Olaparib represents a feasible, biologically-bas...

What is the current status of trial NCT01758731?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 17 participants. The study started on 2012-10-22. Estimated completion is 2018-10-31.

What interventions are being tested in trial NCT01758731?

The interventions under investigation include: Olaparib (DRUG), Radiation Therapy (RADIATION), Cetuximab (DRUG).

Who is sponsoring clinical trial NCT01758731?

This trial is sponsored by University of Colorado, Denver, which has 1,283 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.