Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT01758445 · ClinicalTrials.gov registry record · Phase 2
Proton Radiation for Stage II/III Breast Cancer
A Phase 2 study of Breast Cancer and Breast Neoplasm, sponsored by Proton Collaborative Group.
- Active
- Registry status
- Phase 2
- Development phase
- 220
- Enrollment target
- 5
- Study locations
NCT01758445: Active Phase 2 study of Breast Cancer and Breast Neoplasm, sponsored by Proton Collaborative Group.
NCT01758445 is a Phase 2 study of Breast Cancer and Breast Neoplasm that is active but no longer recruiting, run by Proton Collaborative Group. The registered enrollment target is 220 participants, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (92% lower). The trial reports 5 study locations across 5 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01758445, a Phase 2 study of Breast Cancer and Breast Neoplasm, is active but no longer recruiting, sponsored by Proton Collaborative Group.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 2
- Development phase
- 220 participants
- Enrollment target
- 5
- Study locations
Study Summary
The purpose of this study is to look at the rates of acute and long term adverse events of postoperative proton radiotherapy for complex loco-regional irradiation in women with loco-regionally advanced breast cancer. This study specifically includes longitudinal follow up to assess the incidence of cardiac mortality and second malignant neoplasms at 10 and 15 years following proton therapy(PT).
Conditions Studied
Interventions
- RADIATION Proton Radiotherapy
Study Locations (5)
Illinois
- Northwestern Medicine Chicago Proton Center - Warrenville
Maryland
- Maryland Proton Treatment Center - Baltimore
New Jersey
- Princeton ProCure Managment LLC - Somerset
Oklahoma
- Oklahoma Proton Center - Oklahoma City
Virginia
- Hampton University Proton Therapy Institute - Hampton
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 220 participants |
| Start Date | 2013-02 |
| Est. Completion | 2032-01 |
| Phase | Phase 2 |
What the registry record for NCT01758445 still lists
NCT01758445 is an interventional study that assigns participants to a tested intervention. The registered 220 participants enrollment target is mid-sized for trials with a published cap, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (92% lower).
The record links to 4 conditions, with Breast Cancer appearing as the primary indexed condition, and to 1 intervention - of which Proton Radiotherapy is the first listed.
NCT01758445 lists 5 locations in 5 states (Illinois, Maryland, New Jersey).
Frequently Asked Questions
What is clinical trial NCT01758445 about?
NCT01758445 is a clinical study titled "Proton Radiation for Stage II/III Breast Cancer". The purpose of this study is to look at the rates of acute and long term adverse events of postoperative proton radiotherapy for complex loco-regional irradiation in women with loco-regionally advanced breast cancer. This study specifically includes longitudinal follow up to assess the incidence of ...
What is the current status of trial NCT01758445?
This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 220 participants. The study started on 2013-02. Estimated completion is 2032-01.
What conditions does trial NCT01758445 study?
This clinical trial studies the following conditions: Breast Cancer, Breast Neoplasm, Cancer of the Breast, Breast Tumor.
What interventions are being tested in trial NCT01758445?
The interventions under investigation include: Proton Radiotherapy (RADIATION).
Who is sponsoring clinical trial NCT01758445?
This trial is sponsored by Proton Collaborative Group, which has 10 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01758445 being conducted?
This trial has 5 study locations across Illinois, Maryland, New Jersey, Oklahoma, Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Breast Cancer
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT01758445's enrollment target sits among peer trials
220 342nd of 1224 higher than 881 of 1,224 other Breast Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Breast Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Sequencing Antibody Drug Conjugates in ER+/HER2 LOW/ULTRA LOW MBC
RECRUITING · Phase 2
-
The SAPPHO Study: Sequential Therapy With Curative Intent in de Novo HER2+ Metastatic Breast Cancer
RECRUITING · Phase 2
-
Sacituzumab Govitecan +/- Pembrolizumab in Metastatic TNBC
RECRUITING · Phase 2
-
Evaluation of Talazoparib, a PARP Inhibitor, in Patients With Somatic BRCA Mutant Metastatic Breast Cancer: Genotyping Based Clinical Trial
RECRUITING · Phase 2
-
Endocrine Treatment Alone for Elderly Patients With Estrogen Receptor Positive Operable Breast Cancer and Low Recurrence Score
RECRUITING · Phase 2
-
Precision Medicine in Action: Phase II Trial of Response Adaptive Ablative Pre-operative SPBI (RAPS) and Non-operative Sentinel Lymph Node Biopsy in Patients With Early-stage ER+ Breast Cancer: RAPS Trial
RECRUITING · Phase 2
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT00920972 · 220 participants · Phase 1
Campath/Fludarabine/Melphalan Transplant Conditioning for Non-Malignant Diseases
- NCT01851642 · 220 participants
Lung Disease and Its Affect on the Work of White Blood Cells in the Lungs
- NCT02582021 · 220 participants
WISE CVD - Continuation (WISE HFpEF)
- NCT04067830 · 220 participants · Phase 2
Respiratory Muscle Training Before Surgery in Preventing Lung Complications in Patients With Stage I-IIIB Lung Cancer
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia