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Non-Invasive Treatment of Abdominal Aortic Aneurysm Clinical Trial
NCT01756833 · View on ClinicalTrials.gov ↗
Study Summary
The primary aim of this study is to determine if doxycycline (100 mg bid) will inhibit (by at least 40%) the increase in greatest transverse diameter of small abdominal aortic aneurysms (3.5-5.0 cm in men, 3.5-4.5 cm in women) over a 24-month period of observation in comparison to a placebo-treated control group.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Doxycycline
Study Locations (20)
Arizona
- University of Arizona Medical Center — Tucson
- Carondelet Heart & Vascular Institute — Tucson
California
- University of Southern California — Los Angeles
- Stanford University — Stanford
Florida
- Miami Cardiac and Vascular Institute — Miami
- University of South Florida Health Center — Tampa
Michigan
- University of Michigan Medical Center — Ann Arbor
- McLaren Northern Michigan — Petoskey
Nebraska
- Omaha VAMC — Omaha
- University of Nebraska Medical Center — Omaha
Oregon
- Oregon Health Sciences University — Portland
- Portland VAMC — Portland
Illinois
- Northwestern University Memorial Hospital — Chicago
Maryland
- University of Maryland Medical Center — Baltimore
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 261 participants |
| Start Date | 2013-05 |
| Est. Completion | 2019-07-23 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01756833
The ClinicalTrials.gov registry entry for NCT01756833 describes a study currently listed as completed. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 261 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Maryland, Baltimore, which has 559 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Aneurysm appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT01756833 reports 20 study locations spanning 14 distinct geographic areas — top geographies include Arizona, California, Florida. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT01756833 about?
NCT01756833 is a clinical study titled "Non-Invasive Treatment of Abdominal Aortic Aneurysm Clinical Trial". The primary aim of this study is to determine if doxycycline (100 mg bid) will inhibit (by at least 40%) the increase in greatest transverse diameter of small abdominal aortic aneurysms (3.5-5.0 cm in men, 3.5-4.5 cm in women) over a 24-month period of observation in comparison to a placebo-treated ...
What is the current status of trial NCT01756833?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 261 participants. The study started on 2013-05. Estimated completion is 2019-07-23.
What conditions does trial NCT01756833 study?
This clinical trial studies the following conditions: Aneurysm. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT01756833?
The interventions under investigation include: Placebo (DRUG), Doxycycline (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT01756833?
This trial is sponsored by University of Maryland, Baltimore, which has 559 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT01756833 being conducted?
This trial has 20 study locations across Arizona, California, Florida, Illinois, Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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