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NCT01740817 · ClinicalTrials.gov registry record · NA
A Study to Evaluate the Effect of Lipid Infusion on Toll Like Receptor 4 (TLR4) Signaling
A NA study of Obesity and Diabetes, sponsored by The University of Texas Health Science Center at San Antonio.
- Completed
- Registry status
- NA
- Development phase
- 12
- Enrollment target
- 1
- Study location
NCT01740817: Completed NA study of Obesity and Diabetes, sponsored by The University of Texas Health Science Center at San Antonio.
NCT01740817 is a NA study of Obesity and Diabetes that has completed, run by The University of Texas Health Science Center at San Antonio. The registered enrollment target is 12 participants, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01740817, a NA study of Obesity and Diabetes, has completed, sponsored by The University of Texas Health Science Center at San Antonio.
- COMPLETED
- Registry status
- NA
- Development phase
- 12 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to determine whether a lipid infusion can up-regulate toll-like receptor 4 (TLR4) signaling in human subjects
Primary Outcome
Forty eight hrs after lipid or saline infusion, muscle insulin sensitivity will be measured by insulin clamp. The results are compared to determine whether lipid infusion reduces muscle insulin sensitivity compared to saline infusion.. The M value is defined as the exogenous glucose infusion rate at steady state (i.e, when the exogenous glucose infusion rate is equal to the rate of whole body glucose disposal).
Interventions
- DRUG Saline
- DRUG Intralipid 20%
Study Locations (1)
Texas
- Audie L. Murphy VA Hospital - San Antonio
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 12 participants |
| Start Date | 2008-01 |
| Est. Completion | 2015-09 |
| Phase | NA |
What the finished NCT01740817 record still lists
NCT01740817 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 12 participants, a relatively small participant target, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (99% lower).
The record links to 2 conditions, with Obesity appearing as the primary indexed condition, and to 2 interventions - of which Saline is the first listed.
NCT01740817 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT01740817 about?
NCT01740817 is a clinical study titled "A Study to Evaluate the Effect of Lipid Infusion on Toll Like Receptor 4 (TLR4) Signaling". The purpose of this study is to determine whether a lipid infusion can up-regulate toll-like receptor 4 (TLR4) signaling in human subjects
What is the current status of trial NCT01740817?
This trial is currently completed. It is a NA study. The enrollment target is 12 participants. The study started on 2008-01. Estimated completion is 2015-09.
What conditions does trial NCT01740817 study?
This clinical trial studies the following conditions: Obesity, Diabetes.
What interventions are being tested in trial NCT01740817?
The interventions under investigation include: Saline (DRUG), Intralipid 20% (DRUG).
Who is sponsoring clinical trial NCT01740817?
This trial is sponsored by The University of Texas Health Science Center at San Antonio, which has 378 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01740817 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Obesity
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT01740817's enrollment target sits among peer trials
12 1015th of 1053 higher than 30 of 1,053 other Obesity trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Obesity trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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