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NCT01732770 · ClinicalTrials.gov registry record · Phase 4
Safety and Efficacy Study to Evaluate Denosumab Compared With Zoledronic Acid in Postmenopausal Women With Osteoporosis
A Phase 4 study, sponsored by Amgen.
- Completed
- Registry status
- Phase 4
- Development phase
- 643
- Enrollment target
NCT01732770: Completed Phase 4 study, sponsored by Amgen.
NCT01732770 is a Phase 4 study that has completed, run by Amgen. The registered enrollment target is 643 participants, above the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (24% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01732770, a Phase 4 study, has completed, sponsored by Amgen.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 643 participants
- Enrollment target
Study Summary
This study will compare the effectiveness of denosumab treatment every 6 months with once yearly zoledronic acid treatment on bone mineral density (BMD) at various skeletal sites.
Primary Outcome
Bone mineral density (BMD) of the lumbar spine was measured by dual-energy x-ray absorptiometry (DXA). DXA scans were analyzed by a central imaging facility.
Interventions
- DRUG Zoledronic Acid
- BIOLOGICAL Denosumab
- DRUG Placebo to Denosumab
- DRUG Placebo to Zoledronic Acid
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 643 participants |
| Start Date | 2012-11-07 |
| Est. Completion | 2015-01-07 |
| Phase | Phase 4 |
What the finished NCT01732770 record still lists
NCT01732770 is an interventional study that assigns participants to a tested intervention. The registered 643 participants enrollment target is mid-sized for trials with a published cap, above the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (24% higher).
The record links to 0 conditions, and to 4 interventions - of which Zoledronic Acid is the first listed.
NCT01732770 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01732770 about?
NCT01732770 is a clinical study titled "Safety and Efficacy Study to Evaluate Denosumab Compared With Zoledronic Acid in Postmenopausal Women With Osteoporosis". This study will compare the effectiveness of denosumab treatment every 6 months with once yearly zoledronic acid treatment on bone mineral density (BMD) at various skeletal sites.
What is the current status of trial NCT01732770?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 643 participants. The study started on 2012-11-07. Estimated completion is 2015-01-07.
What interventions are being tested in trial NCT01732770?
The interventions under investigation include: Zoledronic Acid (DRUG), Denosumab (BIOLOGICAL), Placebo to Denosumab (DRUG), Placebo to Zoledronic Acid (DRUG).
Who is sponsoring clinical trial NCT01732770?
This trial is sponsored by Amgen, which has 558 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01732770's enrollment target sits among peer trials
643 126th of 2000 higher than 1,875 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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