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NCT01721473 · ClinicalTrials.gov registry record
Brain Nicotine Receptor Density in Veteran Smokers
A clinical trial, sponsored by VA Office of Research and Development.
- Completed
- Registry status
- 184
- Enrollment target
NCT01721473: Completed study, sponsored by VA Office of Research and Development.
NCT01721473 is a clinical trial that has completed, run by VA Office of Research and Development. The registered enrollment target is 184 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01721473 has completed, sponsored by VA Office of Research and Development.
- COMPLETED
- Registry status
- 184 participants
- Enrollment target
Study Summary
Cigarette smoking is more prevalent among Veterans (27%) than the general U.S. population (21%). Smoking is common among people who use marijuana or caffeine heavily, and the use of menthol cigarettes is becoming increasingly common, affecting approximately 9% of the Veteran population. Recent research by the group and others indicates that heavy marijuana or caffeine use, or the use of predominantly menthol cigarettes, can alter brain nicotinic acetylcholine receptor (nAChR) densities. For the proposed study, brain imaging with PET scanning will be used to determine nicotine receptor densities in Veteran cigarette smokers with and without heavy marijuana or caffeine use, and in menthol and non-menthol Veteran smokers. Results of the proposed research may have implications for improving treatments for Veterans who smoke cigarettes and who have specific drug use co-morbidities or who use menthol cigarettes.
Primary Outcome
Vt/fp values (indicating relative densities of alpha4beta2 nicotinic acetylcholine receptors in different brain regions) in various brain regions - can also be referred to as mL/cm3.
Interventions
- OTHER positron emission tomography scan
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 184 participants |
| Start Date | 2012-01-01 |
| Est. Completion | 2016-06-30 |
What the finished NCT01721473 record still lists
NCT01721473 is an observational study that tracks outcomes without assigning an intervention. The registered 184 participants enrollment target is mid-sized for trials with a published cap.
The record links to 0 conditions, and to 1 intervention - of which positron emission tomography scan is the first listed.
NCT01721473 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01721473 about?
NCT01721473 is a clinical study titled "Brain Nicotine Receptor Density in Veteran Smokers". Cigarette smoking is more prevalent among Veterans (27%) than the general U.S. population (21%). Smoking is common among people who use marijuana or caffeine heavily, and the use of menthol cigarettes is becoming increasingly common, affecting approximately 9% of the Veteran population. Recent resea...
What is the current status of trial NCT01721473?
This trial is currently completed. The enrollment target is 184 participants. The study started on 2012-01-01. Estimated completion is 2016-06-30.
What interventions are being tested in trial NCT01721473?
The interventions under investigation include: positron emission tomography scan (OTHER).
Who is sponsoring clinical trial NCT01721473?
This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.
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