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NCT01718444 · ClinicalTrials.gov registry record · NA
Progestin-induced Endometrial Shedding in PCOS (The PIES in PCOS Study)
A NA study, sponsored by University of Illinois at Chicago.
- Terminated
- Registry status
- NA
- Development phase
- 27
- Enrollment target
NCT01718444: Clinical Trial NA study, sponsored by University of Illinois at Chicago.
NCT01718444 is a NA study that was terminated before completion, run by University of Illinois at Chicago. The registered enrollment target is 27 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01718444, a NA study, was terminated before completion, sponsored by University of Illinois at Chicago.
- TERMINATED
- Registry status
- NA
- Development phase
- 27 participants
- Enrollment target
Study Summary
Progestin-induced endometrial shedding (PIES) followed by clomiphene citrate is fertility treatment of choice in anovulatory women with polycystic ovary syndrome (PCOS). However, some preliminary data suggest that skipping PIES could result in a higher live birth rate. The investigators are performing the first randomized controlled trial to find out if skipping the use of progestin during fertility treatment of anovulatory PCOS women is associated with improved pregnancy and live birth rates compared to the traditional approach of using progestin prior to use of clomiphene citrate.
Primary Outcome
Delivery of a viable infant after 24 weeks of pregnancy
Interventions
- DRUG Clomiphene Citrate
- DRUG Progestin
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 27 participants |
| Start Date | 2015-03 |
| Est. Completion | 2016-06 |
| Phase | NA |
Why NCT01718444 stopped before completion
NCT01718444 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 27 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).
The record links to 0 conditions, and to 2 interventions - of which Clomiphene Citrate is the first listed.
NCT01718444 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01718444 about?
NCT01718444 is a clinical study titled "Progestin-induced Endometrial Shedding in PCOS (The PIES in PCOS Study)". Progestin-induced endometrial shedding (PIES) followed by clomiphene citrate is fertility treatment of choice in anovulatory women with polycystic ovary syndrome (PCOS). However, some preliminary data suggest that skipping PIES could result in a higher live birth rate. The investigators are performi...
What is the current status of trial NCT01718444?
This trial is currently terminated. It is a NA study. The enrollment target is 27 participants. The study started on 2015-03. Estimated completion is 2016-06.
What interventions are being tested in trial NCT01718444?
The interventions under investigation include: Clomiphene Citrate (DRUG), Progestin (DRUG).
Who is sponsoring clinical trial NCT01718444?
This trial is sponsored by University of Illinois at Chicago, which has 430 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01718444's enrollment target sits among peer trials
27 1708th of 2000 higher than 291 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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