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NCT01702519 · ClinicalTrials.gov registry record · Phase 1

A Pharmacokinetic Evaluation of Two Nicotine Patches in Smokers

A Phase 1 study of Smoking, sponsored by GlaxoSmithKline.

Completed
Registry status
Phase 1
Development phase
40
Enrollment target
1
Study location

NCT01702519: Completed Phase 1 study of Smoking, sponsored by GlaxoSmithKline.

NCT01702519 is a Phase 1 study of Smoking that has completed, run by GlaxoSmithKline. The registered enrollment target is 40 participants, below the 455-participant average among 123 other Smoking trials with a reported enrollment target (91% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01702519, a Phase 1 study of Smoking, has completed, sponsored by GlaxoSmithKline.

COMPLETED
Registry status
Phase 1
Development phase
40 participants
Enrollment target
1
Study location

Study Summary

Bioequivalence study to confirm that a NTS with a polyisobutylene (PIB) adhesive from an alternative supplier delivers the same nicotine blood profile as that of the currently approved NTS with a polyisobutylene adhesive from the current supplier.

Primary Outcome

Following randomization, the nicotine patches; reference nicotine patch or test nicotine patch (as per the assigned sequence), were applied on participant's upper back or arm. Area under the plasma concentration time curve from zero and extrapolated to the time of last quantifiable sample was determined by plasma concentration time profile of nicotine. Blood samples were drawn at the following time intervals: immediately pre-dose and at 0.5, 1, 2, 3, 4, 5, 6, 8, 10, 12, 14, 16, 20, 24, 25, 26, 2

Conditions Studied

Interventions

  • DRUG nicotine

Study Locations (1)

Nebraska

  • Celerion NEBRASKA - Lincoln

Trial Details

FieldValue
Enrollment Target 40 participants
Start Date 2012-03
Est. Completion 2012-03
Phase Phase 1
GlaxoSmithKline

1,345 total trials

What the finished NCT01702519 record still lists

NCT01702519 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 455-participant average among 123 other Smoking trials with a reported enrollment target (91% lower).

The record links to 1 condition, with Smoking appearing as the primary indexed condition, and to 1 intervention - of which nicotine is the first listed.

NCT01702519 reports a single indexed study location in Nebraska.

Frequently Asked Questions

What is clinical trial NCT01702519 about?

NCT01702519 is a clinical study titled "A Pharmacokinetic Evaluation of Two Nicotine Patches in Smokers". Bioequivalence study to confirm that a NTS with a polyisobutylene (PIB) adhesive from an alternative supplier delivers the same nicotine blood profile as that of the currently approved NTS with a polyisobutylene adhesive from the current supplier.

What is the current status of trial NCT01702519?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 40 participants. The study started on 2012-03. Estimated completion is 2012-03.

What conditions does trial NCT01702519 study?

This clinical trial studies the following conditions: Smoking.

What interventions are being tested in trial NCT01702519?

The interventions under investigation include: nicotine (DRUG).

Who is sponsoring clinical trial NCT01702519?

This trial is sponsored by GlaxoSmithKline, which has 1,345 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01702519 being conducted?

This trial has 1 study location across Nebraska. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Smoking

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT01702519's enrollment target sits among peer trials

40 102nd of 123 higher than 18 of 123 other Smoking trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Smoking trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01702519, the US trial registry maintained by the National Library of Medicine. NCT01702519 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.